|Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy|
J Schessl, Y Zou, MJ McGrath, BS Cowling, B Maiti, SS Chin, C Sewry, ...
The Journal of clinical investigation 118 (3), 904-912, 2008
|Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly|
MJ McGrath, DL Cottle, MA Nguyen, JM Dyson, ID Coghill, PA Robinson, ...
Journal of Biological Chemistry 281 (11), 7666-7683, 2006
|Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy|
BS Cowling, MJ McGrath, MA Nguyen, DL Cottle, AJ Kee, S Brown, ...
J Cell Biol 183 (6), 1033-1048, 2008
|FHL3 Is an Actin-binding Protein That Regulates α-Actinin-mediated Actin Bundling FHL3 LOCALIZES TO ACTIN STRESS FIBERS AND ENHANCES CELL SPREADING AND STRESS FIBER DISASSEMBLY|
ID Coghill, S Brown, DL Cottle, MJ McGrath, PA Robinson, HH Nandurkar, ...
Journal of Biological Chemistry 278 (26), 24139-24152, 2003
|Four and a half LIM protein 1 gene mutations cause four distinct human myopathies: a comprehensive review of the clinical, histological and pathological features|
BS Cowling, DL Cottle, BR Wilding, CE D’Arcy, CA Mitchell, MJ McGrath
Neuromuscular Disorders 21 (4), 237-251, 2011
|FHL3 binds MyoD and negatively regulates myotube formation|
DL Cottle, MJ McGrath, BS Cowling, ID Coghill, S Brown, CA Mitchell
Journal of cell science 120 (8), 1423-1435, 2007
|c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis|
DL Cottle, K Kretzschmar, PJ Schweiger, SR Quist, HP Gollnick, ...
Cell reports 3 (2), 427-441, 2013
|Regulation of the transcriptional coactivator FHL2 licenses activation of the androgen receptor in castrate-resistant prostate cancer|
MJ McGrath, LC Binge, A Sriratana, H Wang, PA Robinson, D Pook, ...
Cancer research 73 (16), 5066-5079, 2013
|BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions|
K Kretzschmar, DL Cottle, G Donati, MF Chiang, SR Quist, HP Gollnick, ...
Stem Cell Reports 3 (4), 620-633, 2014
|INPP5E interacts with AURKA, linking phosphoinositide signalling to primary cilium stability|
OV Plotnikova, S Seo, DL Cottle, S Conduit, S Hakim, JM Dyson, ...
Journal of Cell Science 128 (2), 364-372, 2015
|Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation|
MA Berta, CM Baker, DL Cottle, FM Watt
EMBO molecular medicine 2 (1), 16-25, 2009
|The Androgen Receptor Antagonises Wnt/Beta-Catenin Signalling in Epidermal Stem Cells|
K Kretzschmar, DL Cottle, PJ Schweiger, FM Watt
Journal of Investigative Dermatology,10.1038/jid.2015.242, 2015
|Keratin 76 Is Required for Tight Junction Function and Maintenance of the Skin Barrier|
T DiTommaso, DL Cottle, HB Pearson, H Schlüter, P Kaur, PO Humbert, ...
Plos Genetics 10 (10), e1004706, 2014
|SLIMMER (FHL1B/KyoT3) interacts with the proapoptotic protein Siva-1 (CD27BP) and delays skeletal myoblast apoptosis|
DL Cottle, MJ McGrath, BR Wilding, BS Cowling, JM Kane, CE D'Arcy, ...
Journal of Biological Chemistry 284 (39), 26964-26977, 2009
|Fetal inhibition of inflammation improves disease phenotypes in Harlequin Ichthyosis|
DL Cottle, GMA Ursino, S Chi Ieng Ip, LK Jones, T DiTommaso, ...
Human Molecular Genetics 24 (2), 436-49, 2015
|Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse|
T DiTommaso, LK Jones, DL Cottle, TWMG Program, AK Gerdin, ...
Plos Genetics 10 (10), e1004705, 2014
|Regulation of PDGFC signalling and extracellular matrix composition by FREM1 in mice|
F Wiradjaja, DL Cottle, L Jones, I Smyth
Disease models & mechanisms 6 (6), 1426-1433, 2013
|p53 activity contributes to defective interfollicular epidermal differentiation in hyperproliferative murine skin|
DL Cottle, K Kretzschmar, HP Gollnick, SR Quist
British Journal of Dermatology 174 (1), 204-208, 2016
|Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis|
SJ Goldie, DL Cottle, FH Tan, S Roslan, S Srivastava, R Brady, ...
Cell Death & Disease 9 (1072), 2018
|Treatment of skin conditions|
I Smyth, D Cottle, G Ursino
US Patent App. 15/557,405, 2018