Low diversity gut microbiota dysbiosis: drivers, functional implications and recovery M Kriss, KZ Hazleton, NM Nusbacher, CG Martin, CA Lozupone Current opinion in microbiology 44, 34-40, 2018 | 342 | 2018 |
Purine and pyrimidine pathways as targets in Plasmodium falciparum M Belen Cassera, Y Zhang, K Z Hazleton, V L Schramm Current topics in medicinal chemistry 11 (16), 2103-2115, 2011 | 168 | 2011 |
Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase KZ Hazleton, MC Ho, MB Cassera, K Clinch, DR Crump, I Rosario, ... Chemistry & biology 19 (6), 721-730, 2012 | 79 | 2012 |
Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model MB Cassera, KZ Hazleton, EF Merino, N Obaldia III, MC Ho, AS Murkin, ... PLoS One 6 (11), e26916, 2011 | 78 | 2011 |
Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum MB Cassera, KZ Hazleton, PM Riegelhaupt, EF Merino, M Luo, ... Journal of biological chemistry 283 (47), 32889-32899, 2008 | 68 | 2008 |
Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase K Clinch, DR Crump, GB Evans, KZ Hazleton, JM Mason, VL Schramm, ... Bioorganic & medicinal chemistry 21 (17), 5629-5646, 2013 | 49 | 2013 |
Structural characterization of the fusion of two pentapeptide repeat proteins, Np275 and Np276, from Nostoc punctiforme: Resurrection of an ancestral protein MW Vetting, SS Hegde, KZ Hazleton, JS Blanchard Protein science 16 (4), 755-760, 2007 | 37 | 2007 |
Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1 PM Riegelhaupt, MB Cassera, RFG Fröhlich, KZ Hazleton, JJ Hefter, ... Molecular and biochemical parasitology 169 (1), 40-49, 2010 | 35 | 2010 |
Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases Y Zhang, GB Evans, K Clinch, DR Crump, LD Harris, RFG Fröhlich, ... Journal of Biological Chemistry 288 (48), 34746-34754, 2013 | 33 | 2013 |
Gastric injury secondary to button battery ingestions: a retrospective multicenter review RT Khalaf, W Ruan, S Orkin, M Wilsey, DS Fishman, D Mallon, Z Pan, ... Gastrointestinal endoscopy 92 (2), 276-283, 2020 | 20 | 2020 |
Multiple-ascending-dose phase 1 clinical study of the safety, tolerability, and pharmacokinetics of CRS3123, a narrow-spectrum agent with minimal disruption of normal gut … BK Lomeli, H Galbraith, J Schettler, GA Saviolakis, W El-Amin, B Osborn, ... Antimicrobial agents and chemotherapy 64 (1), 10.1128/aac. 01395-19, 2019 | 18 | 2019 |
Anopheles gambiae Purine Nucleoside Phosphorylase: Catalysis, Structure, and Inhibition, EA Taylor, A Rinaldo-Matthis, L Li, M Ghanem, KZ Hazleton, MB Cassera, ... Biochemistry 46 (43), 12405-12415, 2007 | 14 | 2007 |
Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice KZ Hazleton, CG Martin, DJ Orlicky, KL Arnolds, NM Nusbacher, ... npj Biofilms and Microbiomes 8 (1), 15, 2022 | 6 | 2022 |
2019 gut microbiota for health world summit GM Fuhler, GA Hecht, SE Foley, AC Lebron, K Hazleton Gastroenterology 158 (1), 28-31, 2020 | 4 | 2020 |
Dietary fat and fiber impacts intestinal microbiome resilience to antibiotics and Clostridoides difficile infection in mice KZ Hazleton, CG Martin, KL Arnolds, NM Nusbacher, N Moreno-Huizar, ... BioRxiv, 828939, 2019 | 1 | 2019 |
A Multimodal Intervention to Reduce C. difficile Infections and Stool Testing JM Cotter, CL Stokes, S Tong, M Birkholz, J Child, C Cost, R Coughlin, ... Pediatrics, e2023061981, 2024 | | 2024 |
EMR-based clinical decision support to address rising Clostridioides difficile rates in a pediatric hematology/oncology/BMT unit. C Stokes, J Cotter, CR Cost, KMCOT Dorris, V Lugo, J Child, R Coughlin, ... Journal of Clinical Oncology 40 (28_suppl), 383-383, 2022 | | 2022 |
A NOVEL MULTI-OMICS ANALYSIS (VOLARE) REVEALS LIVER-DISEASE SPECIFIC ASSOCIATIONS BETWEEN GUT MICROBIOME, PORTAL METABOLOME, AND HEPATIC GENE EXPRESSION IN HUMANS MS Kriss, J Siebert, K Hazleton, J Klawitter, E Pomfret, JJ Pomposelli, ... HEPATOLOGY 70, 1153A-1153A, 2019 | | 2019 |
Purine salvage as an antimalarial target KZ Hazleton Yeshiva University, 2011 | | 2011 |
Metabolic and molecular evidence of adenosine kinase activity in Plasmodium falciparum. MB Cassera, EF Merino, KZ Hazleton, JM Carlton, VL Schramm INTERNATIONAL JOURNAL FOR PARASITOLOGY 38, S69-S69, 2008 | | 2008 |