Molecular basis for universal HLA-A* 0201–restricted CD8+ T-cell immunity against influenza viruses SA Valkenburg, TM Josephs, EB Clemens, EJ Grant, THO Nguyen, ... Proceedings of the National Academy of Sciences 113 (16), 4440-4445, 2016 | 106 | 2016 |
Reversed T cell receptor docking on a major histocompatibility class I complex limits involvement in the immune response S Gras, J Chadderton, CM Del Campo, C Farenc, F Wiede, TM Josephs, ... Immunity 45 (4), 749-760, 2016 | 83 | 2016 |
International union of basic and clinical pharmacology. CVIII. Calcium-sensing receptor nomenclature, pharmacology, and function K Leach, FM Hannan, TM Josephs, AN Keller, TC Møller, DT Ward, ... Pharmacological Reviews 72 (3), 558-604, 2020 | 81 | 2020 |
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms TM Josephs, MJ Belousoff, YL Liang, SJ Piper, J Cao, DJ Garama, ... Science 372 (6538), eabf7258, 2021 | 63 | 2021 |
Broad CD8+ T cell cross-recognition of distinct influenza A strains in humans EJ Grant, TM Josephs, L Loh, EB Clemens, S Sant, M Bharadwaj, W Chen, ... Nature communications 9 (1), 5427, 2018 | 52 | 2018 |
Fasting-induced adipose factor identified as a key adipokine that is up-regulated in white adipose tissue during pregnancy and lactation in the rat T Josephs, H Waugh, I Kokay, D Grattan, M Thompson Journal of Endocrinology 194 (2), 305-312, 2007 | 49 | 2007 |
Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats TM Visarius, H Bähler, A Küpfer, T Cerny, BH Lauterburg Drug Metabolism and Disposition 26 (3), 193-196, 1998 | 48 | 1998 |
Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination TM Josephs, MD Liptak, G Hughes, A Lo, RM Smith, SM Wilbanks, ... JBIC Journal of Biological Inorganic Chemistry 18, 289-297, 2013 | 44 | 2013 |
Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release TM Josephs, IM Morison, CL Day, SM Wilbanks, EC Ledgerwood Biochemical Journal 458 (2), 259-265, 2014 | 42 | 2014 |
A structural basis for amylin receptor phenotype J Cao, MJ Belousoff, YL Liang, RM Johnson, TM Josephs, MM Fletcher, ... Science 375 (6587), eabm9609, 2022 | 34 | 2022 |
Molecular challenges imposed by MHC-I restricted long epitopes on T cell immunity TM Josephs, EJ Grant, S Gras Biological chemistry 398 (9), 1027-1036, 2017 | 30 | 2017 |
AT cell receptor locus harbors a malaria-specific immune response gene N Van Braeckel-Budimir, S Gras, K Ladell, TM Josephs, L Pewe, ... Immunity 47 (5), 835-847. e4, 2017 | 29 | 2017 |
Lack of heterologous cross-reactivity toward HLA-A* 02: 01 restricted viral epitopes is underpinned by distinct αβT cell receptor signatures EJ Grant, TM Josephs, SA Valkenburg, L Wooldridge, M Hellard, ... Journal of Biological Chemistry 291 (47), 24335-24351, 2016 | 25 | 2016 |
Identification of global and ligand-specific calcium sensing receptor activation mechanisms AN Keller, I Kufareva, TM Josephs, J Diao, VT Mai, AD Conigrave, ... Molecular pharmacology 93 (6), 619-630, 2018 | 23 | 2018 |
HIV-1–specific CD8 T cells exhibit limited cross-reactivity during acute infection VY Du, A Bansal, J Carlson, JF Salazar-Gonzalez, MG Salazar, K Ladell, ... The Journal of Immunology 196 (8), 3276-3286, 2016 | 23 | 2016 |
Negative allosteric modulators of the human calcium‐sensing receptor bind to overlapping and distinct sites within the 7‐transmembrane domain TM Josephs, AN Keller, E Khajehali, A DeBono, CJ Langmead, ... British journal of pharmacology 177 (8), 1917-1930, 2020 | 17 | 2020 |
Therapeutic opportunities of targeting allosteric binding sites on the calcium-sensing receptor J Diao, A DeBono, TM Josephs, JE Bourke, B Capuano, KJ Gregory, ... ACS Pharmacology & Translational Science 4 (2), 666-679, 2021 | 15 | 2021 |
Interspecies Variation in the Functional Consequences of Mutation of Cytochrome c TM Josephs, ME Hibbs, L Ong, IM Morison, EC Ledgerwood PloS one 10 (6), e0130292, 2015 | 11 | 2015 |
A STAT3 protein complex required for mitochondrial mRNA stability and cancer CD Fernando, WSN Jayasekara, C Inampudi, MRJ Kohonen-Corish, ... Cell Reports 42 (9), 2023 | 2 | 2023 |
Personalised medicines for familial hypercalcemia and hyperparathyroidism TM Josephs, F Zhang, LV Dinh, AN Keller, AD Conigrave, B Capuano, ... Journal of Molecular Endocrinology 69 (1), 243-257, 2022 | 2 | 2022 |