| Small-molecule control of protein function through Staudinger reduction J Luo, Q Liu, K Morihiro, A Deiters Nature chemistry 8 (11), 1027-1034, 2016 | 113 | 2016 |
| Biological applications of xeno nucleic acids K Morihiro, Y Kasahara, S Obika Molecular BioSystems 13 (2), 235-245, 2017 | 110 | 2017 |
| Effect of 3′-end capping of aptamer with various 2′, 4′-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamers Y Kasahara, S Kitadume, K Morihiro, M Kuwahara, H Ozaki, H Sawai, ... Bioorganic & medicinal chemistry letters 20 (5), 1626-1629, 2010 | 57 | 2010 |
| Small molecule release and activation through DNA computing K Morihiro, N Ankenbruck, B Lukasak, A Deiters Journal of the American Chemical Society 139 (39), 13909-13915, 2017 | 51 | 2017 |
| Hydrogen peroxide-triggered gene silencing in mammalian cells through boronated antisense oligonucleotides S Mori, K Morihiro, T Okuda, Y Kasahara, S Obika Chemical science 9 (5), 1112-1118, 2018 | 40 | 2018 |
| Aryl azides as phosphine-activated switches for small molecule function B Lukasak, K Morihiro, A Deiters Scientific Reports 9 (1), 1470, 2019 | 29 | 2019 |
| Selenomethylene locked nucleic acid enables reversible hybridization in response to redox changes. K Morihiro, T Kodama, Y Moai, RN Veedu, S Obika Angewandte Chemie International Edition 52 (19), 2013 | 26 | 2013 |
| Phosphine‐Activated Lysine Analogues for Fast Chemical Control of Protein Subcellular Localization and Protein SUMOylation JS Wesalo, J Luo, K Morihiro, J Liu, A Deiters ChemBioChem 21 (1-2), 141-148, 2020 | 24 | 2020 |
| Consecutive incorporation of functionalized nucleotides with amphiphilic side chains by novel KOD polymerase mutant H Hoshino, Y Kasahara, H Fujita, M Kuwahara, K Morihiro, S Tsunoda, ... Bioorganic & Medicinal Chemistry Letters 26 (2), 530-533, 2016 | 21 | 2016 |
| C5-Azobenzene-substituted 2'-Deoxyuridine-containing Oligodeoxynucleotides for Photo-Switching Hybridization S Mori, K Morihiro, S Obika Molecules 19 (4), 5109-5118, 2014 | 21 | 2014 |
| A hydrogen peroxide activatable gemcitabine prodrug for the selective treatment of pancreatic ductal adenocarcinoma K Matsushita, T Okuda, S Mori, M Konno, H Eguchi, A Asai, J Koseki, ... ChemMedChem 14 (15), 1384-1391, 2019 | 18 | 2019 |
| Benzylidene acetal type bridged nucleic acids: changes in properties upon cleavage of the bridge triggered by external stimuli K Morihiro, T Kodama, S Obika Chemistry–A European Journal 17 (28), 7918-7926, 2011 | 16 | 2011 |
| Identification of nucleobase chemical modifications that reduce the hepatotoxicity of gapmer antisense oligonucleotides T Yoshida, K Morihiro, Y Naito, A Mikami, Y Kasahara, T Inoue, S Obika Nucleic Acids Research 50 (13), 7224-7234, 2022 | 15 | 2022 |
| anti–syn Unnatural Base Pair Enables Alphabet-Expanded DNA Self-Assembly K Morihiro, Y Moriyama, Y Nemoto, H Osumi, A Okamoto Journal of the American Chemical Society 143 (35), 14207-14217, 2021 | 15 | 2021 |
| Floxuridine oligomers activated under hypoxic environment K Morihiro, T Ishinabe, M Takatsu, H Osumi, T Osawa, A Okamoto Journal of the American Chemical Society 143 (9), 3340-3347, 2021 | 15 | 2021 |
| C5-azobenzene-functionalized locked nucleic acid uridine: isomerization properties, hybridization ability, and enzymatic stability K Morihiro, O Hasegawa, S Mori, S Tsunoda, S Obika Organic & Biomolecular Chemistry 13 (18), 5209-5214, 2015 | 15 | 2015 |
| Light-triggered strand exchange reaction using the change in the hydrogen bonding pattern of a nucleobase analogue K Morihiro, T Kodama, R Waki, S Obika Chemical Science 5 (2), 744-750, 2014 | 15 | 2014 |
| Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases M Wheeler, A Chardon, A Goubet, K Morihiro, SY Tsan, SL Edwards, ... Chemical communications 48 (89), 11020-11022, 2012 | 14 | 2012 |
| Synthesis of Light‐Responsive Bridged Nucleic Acid and Changes in Affinity with Complementary ssRNA K Morihiro, T Kodama, M Nishida, T Imanishi, S Obika ChemBioChem 10 (11), 1784-1788, 2009 | 14 | 2009 |
| Systematic evaluation of biophysical and functional characteristics of selenomethylene-locked nucleic acid-mediated inhibition of miR-21 S Nahar, A Singh, K Morihiro, Y Moai, T Kodama, S Obika, S Maiti Biochemistry 55 (50), 7023-7032, 2016 | 12 | 2016 |
Alexander DeitersProfessor of Chemistry at the University of PittsburghVerified email at pitt.edu
