| Mdm2 promotes the rapid degradation of p53 Y Haupt, R Maya, A Kazaz, M Oren Nature 387 (6630), 296-299, 1997 | 5542 | 1997 |
| Apoptosis-the p53 network S Haupt, M Berger, Z Goldberg, Y Haupt Journal of cell science 116 (20), 4077-4085, 2003 | 1649 | 2003 |
| The cellular response to p53: the decision between life and death RV Sionov, Y Haupt Oncogene 18 (45), 6145-6157, 1999 | 822 | 1999 |
| Induction of apoptosis in HeLa cells by trans-activation-deficient p53. Y Haupt, S Rowan, E Shaulian, KH Vousden, M Oren Genes & development 9 (17), 2170-2183, 1995 | 761 | 1995 |
| Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice Y Haupt, WS Alexander, G Barri, SP Klinken, JM Adams Cell 65 (5), 753-763, 1991 | 721 | 1991 |
| c-Jun and p53 activity is modulated by SUMO-1 modification S Müller, M Berger, F Lehembre, JS Seeler, Y Haupt, A Dejean Journal of Biological Chemistry 275 (18), 13321-13329, 2000 | 532 | 2000 |
| Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2 T Unger, T Juven‐Gershon, E Moallem, M Berger, RV Sionov, G Lozano, ... The EMBO journal, 1999 | 486 | 1999 |
| Specific loss of apoptotic but not cell‐cycle arrest function in a human tumor derived p53 mutant. S Rowan, RL Ludwig, Y Haupt, S Bates, X Lu, M Oren, KH Vousden The EMBO journal 15 (4), 827-838, 1996 | 387 | 1996 |
| Clinical overview of MDM2/X-targeted therapies A Burgess, KM Chia, S Haupt, D Thomas, Y Haupt, E Lim Frontiers in oncology 6, 7, 2016 | 377 | 2016 |
| A functional p53-responsive intronic promoter is contained within the human mdm2 gene A Zauberman, D Flusberg, Y Haupt, Y Barak, M Oren Nucleic acids research 23 (14), 2584-2592, 1995 | 374 | 1995 |
| A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis P Friedlander, Y Haupt, C Prives, M Oren Molecular and cellular biology, 1996 | 363 | 1996 |
| MDM4 is a key therapeutic target in cutaneous melanoma A Gembarska, F Luciani, C Fedele, EA Russell, M Dewaele, S Villar, ... Nature medicine 18 (8), 1239-1247, 2012 | 357 | 2012 |
| Cell type‐specific inhibition of p53‐mediated apoptosis by mdm2. Y Haupt, Y Barak, M Oren The EMBO journal 15 (7), 1596-1606, 1996 | 323 | 1996 |
| Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis S Masaldan, SAS Clatworthy, C Gamell, PM Meggyesy, AT Rigopoulos, ... Redox biology 14, 100-115, 2018 | 307 | 2018 |
| Tumour suppression by p53: the importance of apoptosis and cellular senescence V Zuckerman, K Wolyniec, RV Sionov, S Haupt, Y Haupt The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 285 | 2009 |
| Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation DS Liu, CP Duong, S Haupt, KG Montgomery, CM House, WJ Azar, ... Nature communications 8 (1), 14844, 2017 | 283 | 2017 |
| AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, ... Oncogene 31 (15), 1949-1962, 2012 | 276 | 2012 |
| Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation Z Goldberg, RV Sionov, M Berger, Y Zwang, R Perets, RA Van Etten, ... The EMBO journal 21 (14), 3715-3727, 2002 | 253 | 2002 |
| bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis. Y Haupt, ML Bath, AW Harris, JM Adams Oncogene 8 (11), 3161-3164, 1993 | 244 | 1993 |
| Mutations in serines 15 and 20 of human p53 impair its apoptotic activity T Unger, RV Sionov, E Moallem, CL Yee, PM Howley, M Oren, Y Haupt Oncogene 18 (21), 3205-3212, 1999 | 236 | 1999 |
Sue HauptSenior Research FellowVerified email at petermac.org
Sue HauptSenior Research FellowVerified email at petermac.org