Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS T Nomura, CG Cranfield, E Deplazes, DM Owen, A Macmillan, AR Battle, ... Proceedings of the National Academy of Sciences 109 (22), 8770-8775, 2012 | 175 | 2012 |
Widespread convergence in toxin resistance by predictable molecular evolution B Ujvari, NR Casewell, K Sunagar, K Arbuckle, W Wüster, N Lo, ... Proceedings of the National Academy of Sciences 112 (38), 11911-11916, 2015 | 119 | 2015 |
A combined theoretical and experimental study of the structure and vibrational absorption, vibrational circular dichroism, Raman and Raman optical activity spectra of the L … E Deplazes, W Van Bronswijk, F Zhu, LD Barron, S Ma, LA Nafie, ... Theoretical Chemistry Accounts 119 (1), 155-176, 2008 | 82 | 2008 |
Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1. 7 ST Henriques, E Deplazes, N Lawrence, O Cheneval, S Chaousis, ... Journal of Biological Chemistry 291 (33), 17049-17065, 2016 | 66 | 2016 |
Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations E Deplazes, M Louhivuori, D Jayatilaka, SJ Marrink, B Corry PLOS Computational Biology 8 (9), e1002683, 2012 | 46 | 2012 |
Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1. 7 AJ Agwa, N Lawrence, E Deplazes, O Cheneval, RM Chen, DJ Craik, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (5), 835-844, 2017 | 43 | 2017 |
Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a NJ Saez, E Deplazes, B Cristofori‐Armstrong, IR Chassagnon, X Lin, ... British journal of pharmacology 172 (20), 4985-4995, 2015 | 38 | 2015 |
Bacterial mechanosensitive channels: models for studying mechanosensory transduction B Martinac, T Nomura, G Chi, E Petrov, PR Rohde, AR Battle, A Foo, ... Antioxidants & redox signaling 20 (6), 952-969, 2014 | 38 | 2014 |
Resolutions of the Coulomb operator SA Varganov, ATB Gilbert, E Deplazes, PMW Gill The Journal of chemical physics 128 (20), 201104, 2008 | 37 | 2008 |
The role of structure and biophysical properties in the pleiotropic effects of statins C Murphy, E Deplazes, CG Cranfield, A Garcia International journal of molecular sciences 21 (22), 8745, 2020 | 28 | 2020 |
Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating E Deplazes, ST Henriques, JJ Smith, GF King, DJ Craik, AE Mark, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (4), 872-882, 2016 | 28 | 2016 |
Characterisation of the structure and oligomerisation of islet amyloid polypeptides (IAPP): a review of molecular dynamics simulation studies SJ Moore, K Sonar, P Bharadwaj, E Deplazes, RL Mancera Molecules 23 (9), 2142, 2018 | 24 | 2018 |
ExiFRET: flexible tool for understanding FRET in complex geometries E Deplazes, D Jayatilaka, B Corry Journal of Biomedical Optics 17 (1), 011005, 2012 | 18 | 2012 |
Testing the use of molecular dynamics to simulate fluorophore motions and FRET E Deplazes, D Jayatilaka, B Corry Physical Chemistry Chemical Physics 13 (23), 11045-11054, 2011 | 18 | 2011 |
The biological and biophysical properties of the spider peptide gomesin JD Tanner, E Deplazes, RL Mancera Molecules 23 (7), 1733, 2018 | 17 | 2018 |
Molecular dynamics simulation of small molecules interacting with biological membranes C Martinotti, L Ruiz‐Perez, E Deplazes, RL Mancera ChemPhysChem 21 (14), 1486-1514, 2020 | 14 | 2020 |
The effect of hydronium ions on the structure of phospholipid membranes E Deplazes, D Poger, B Cornell, CG Cranfield Physical Chemistry Chemical Physics 20 (1), 357-366, 2018 | 14 | 2018 |
Gomesin peptides prevent proliferation and lead to the cell death of devil facial tumour disease cells MA Fernandez-Rojo, E Deplazes, SS Pineda, A Brust, T Marth, P Wilhelm, ... Cell death discovery 4 (1), 1-11, 2018 | 13 | 2018 |
Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy E Deplazes, SL Begg, JH Van Wonderen, R Campbell, B Kobe, JC Paton, ... Biophysical chemistry 207, 51-60, 2015 | 10 | 2015 |
Role of ion–phospholipid interactions in Zwitterionic phospholipid bilayer ion permeation E Deplazes, BD Tafalla, CG Cranfield, A Garcia The journal of physical chemistry letters 11 (15), 6353-6358, 2020 | 9 | 2020 |