RACK1, A multifaceted scaffolding protein: Structure and function DR Adams, D Ron, PA Kiely Cell communication and signaling 9, 1-24, 2011 | 493 | 2011 |
Inclusion of the mesentery in ileocolic resection for Crohn’s disease is associated with reduced surgical recurrence CJ Coffey, MG Kiernan, SM Sahebally, A Jarrar, JP Burke, PA Kiely, ... Journal of Crohn's and Colitis 12 (10), 1139-1150, 2018 | 277 | 2018 |
Optimising parameters for the differentiation of SH-SY5Y cells to study cell adhesion and cell migration S Dwane, E Durack, PA Kiely BMC research notes 6, 1-11, 2013 | 194 | 2013 |
Communication, collaboration and contagion:“Virtualisation” of anatomy during COVID‐19 KG Byrnes, PA Kiely, CP Dunne, KW McDermott, JC Coffey Clinical anatomy 34 (1), 82-89, 2021 | 189 | 2021 |
RACK1 is an insulin-like growth factor 1 (IGF-1) receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death PA Kiely, A Sant, R O'Connor Journal of Biological Chemistry 277 (25), 22581-22589, 2002 | 167 | 2002 |
Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of … DA Buckley, A Cheng, PA Kiely, ML Tremblay, R O'Connor Molecular and cellular biology 22 (7), 1998-2010, 2002 | 154 | 2002 |
Deubiquitination of NF-κB by ubiquitin-specific protease-7 promotes transcription A Colleran, PE Collins, C O’Carroll, A Ahmed, X Mao, B McManus, ... Proceedings of the National Academy of Sciences 110 (2), 618-623, 2013 | 150 | 2013 |
Insulin-like growth factor I controls a mutually exclusive association of RACK1 with protein phosphatase 2A and β1 integrin to promote cell migration PA Kiely, D O'Gorman, K Luong, D Ron, R O'Connor Molecular and cellular biology 26 (11), 4041-4051, 2006 | 129 | 2006 |
Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase PA Kiely, GS Baillie, R Barrett, DA Buckley, DR Adams, MD Houslay, ... Journal of Biological Chemistry 284 (30), 20263-20274, 2009 | 121 | 2009 |
Mutant p53: a novel target for the treatment of patients with triple‐negative breast cancer? NC Synnott, A Murray, PM McGowan, M Kiely, PA Kiely, N O'donovan, ... International journal of cancer 140 (1), 234-246, 2017 | 120 | 2017 |
Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis E Kerr, C Holohan, KM McLaughlin, J Majkut, S Dolan, K Redmond, ... Cell Death & Differentiation 19 (8), 1317-1327, 2012 | 109 | 2012 |
Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth G Loughran, NC Healy, PA Kiely, M Huigsloot, NL Kedersha, R O'Connor Molecular biology of the cell 16 (4), 1811-1822, 2005 | 108 | 2005 |
RACK1-mediated integration of adhesion and insulin-like growth factor I (IGF-I) signaling and cell migration are defective in cells expressing an IGF-I receptor mutated at … PA Kiely, M Leahy, D O'Gorman, R O'Connor Journal of Biological Chemistry 280 (9), 7624-7633, 2005 | 103 | 2005 |
PP2A: the wolf in sheep’s clothing? M Kiely, PA Kiely Cancers 7 (2), 648-669, 2015 | 101 | 2015 |
Factors associated with absenteeism, presenteeism and activity impairment in patients in the first years of RA N Bansback, W Zhang, D Walsh, P Kiely, R Williams, D Guh, A Anis, ... Rheumatology 51 (2), 375-384, 2012 | 101 | 2012 |
Tyrosine 302 in RACK1 is essential for insulin-like growth factor-I-mediated competitive binding of PP2A and β1 integrin and for tumor cell proliferation and migration PA Kiely, GS Baillie, MJ Lynch, MD Houslay, R O'Connor Journal of Biological Chemistry 283 (34), 22952-22961, 2008 | 92 | 2008 |
Using real-time impedance-based assays to monitor the effects of fibroblast-derived media on the adhesion, proliferation, migration and invasion of colon cancer cells CM Dowling, C Herranz Ors, PA Kiely Bioscience reports 34 (4), e00126, 2014 | 90 | 2014 |
Enhanced cell viability in hyaluronic acid coated poly (lactic-co-glycolic acid) porous scaffolds within microfluidic channels F Zamboni, M Keays, S Hayes, AB Albadarin, GM Walker, PA Kiely, ... International journal of pharmaceutics 532 (1), 595-602, 2017 | 75 | 2017 |
Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet—fibrinogen interaction DK Shanley, PA Kiely, K Golla, S Allen, K Martin, RT O’Riordan, M Ball, ... PloS one 8 (2), e57491, 2013 | 69 | 2013 |
Inhibition of transcription by B cell Leukemia 3 (Bcl-3) protein requires interaction with nuclear factor κB (NF-κB) p50 PE Collins, PA Kiely, RJ Carmody Journal of Biological Chemistry 289 (10), 7059-7067, 2014 | 61 | 2014 |