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John W Huffman
John W Huffman
Verified email at clemson.edu
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Year
Cannabinoids control spasticity and tremor in a multiple sclerosis model
D Baker, G Pryce, JL Croxford, P Brown, RG Pertwee, JW Huffman, ...
Nature 404 (6773), 84-87, 2000
7612000
Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor
C Sánchez, ML de Ceballos, TG del Pulgar, D Rueda, C Corbacho, ...
Cancer research 61 (15), 5784-5789, 2001
5242001
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
ML Casanova, C Blázquez, J Martínez-Palacio, C Villanueva, ...
The Journal of clinical investigation 111 (1), 43-50, 2003
5232003
Inhibition of tumor angiogenesis by cannabinoids
C Blázquez, ML Casanova, A Planas, T Gómez del Pulgar, C Villanueva, ...
The FASEB journal 17 (3), 1-16, 2003
3452003
Design, synthesis and pharmacology of cannabimimetic indoles
JW Huffman, D Dai, BR Martin, DR Compton
Bioorganic & Medicinal Chemistry Letters 4 (4), 563-566, 1994
3451994
Structure–activity relationships for 1-alkyl-3-(1-naphthoyl) indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New …
JW Huffman, G Zengin, MJ Wu, J Lu, G Hynd, K Bushell, ALS Thompson, ...
Bioorganic & medicinal chemistry 13 (1), 89-112, 2005
3302005
Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding
MM Aung, G Griffin, JW Huffman, MJ Wu, C Keel, B Yang, VM Showalter, ...
Drug and alcohol dependence 60 (2), 133-140, 2000
3172000
3-(1′, 1′-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor
JW Huffman, J Liddle, S Yu, MM Aung, ME Abood, JL Wiley, BR Martin
Bioorganic & medicinal chemistry 7 (12), 2905-2914, 1999
3151999
JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB1 receptor agonist
BK Atwood, J Huffman, A Straiker, K Mackie
British journal of pharmacology 160 (3), 585-593, 2010
3022010
Structure-activity relationships of indole-and pyrrole-derived cannabinoids
JL Wiley, DR Compton, D Dai, JAH Lainton, M Phillips, JW Huffman, ...
Journal of Pharmacology and Experimental Therapeutics 285 (3), 995-1004, 1998
2941998
Cannabinoid‐2 receptor mediates protection against hepatic ischemia/reperfusion injury
S Bátkai, D Osei‐Hyiaman, H Pan, O El‐Assal, M Rajesh, ...
The FASEB Journal 21 (8), 1788-1800, 2007
2862007
CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion
M Rajesh, P Mukhopadhyay, S Bátkai, G Hasko, L Liaudet, JW Huffman, ...
American Journal of Physiology-Heart and Circulatory Physiology 293 (4 …, 2007
2782007
Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes
JW Huffman, LW Padgett
Current medicinal chemistry 12 (12), 1395-1411, 2005
2572005
Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals
G Griffin, SR Fernando, RA Ross, NG McKay, MLJ Ashford, D Shire, ...
European journal of pharmacology 339 (1), 53-61, 1997
2181997
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor
JW Huffman, S Yu, V Showalter, ME Abood, JL Wiley, DR Compton, ...
Journal of medicinal chemistry 39 (20), 3875-3877, 1996
2021996
1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles
JW Huffman, PV Szklennik, A Almond, K Bushell, DE Selley, H He, ...
Bioorganic & Medicinal Chemistry Letters 15 (18), 4110-4113, 2005
1892005
3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor
JW Huffman, R Mabon, MJ Wu, J Lu, R Hart, DP Hurst, PH Reggio, ...
Bioorganic & medicinal chemistry 11 (4), 539-549, 2003
1842003
Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids
JL Wiley, JA Marusich, JW Huffman
Life sciences 97 (1), 55-63, 2014
1782014
Cannabimimetic indoles, pyrroles and indenes
JW Huffman
Current medicinal chemistry 6, 705-720, 1999
1671999
CB2 cannabinoid receptor agonists attenuate TNF‐α‐induced human vascular smooth muscle cell proliferation and migration
M Rajesh, P Mukhopadhyay, G Hasko, JW Huffman, K Mackie, P Pacher
British journal of pharmacology 153 (2), 347-357, 2008
1652008
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