John W Huffman
John W Huffman
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Cannabinoids control spasticity and tremor in a multiple sclerosis model
D Baker, G Pryce, JL Croxford, P Brown, RG Pertwee, JW Huffman, ...
Nature 404 (6773), 84-87, 2000
Inhibition of Glioma Growth in Vivo by Selective Activation of the CB2 Cannabinoid Receptor
C Sánchez, ML de Ceballos, TG del Pulgar, D Rueda, C Corbacho, ...
Cancer research 61 (15), 5784-5789, 2001
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
ML Casanova, C Blázquez, J Martínez-Palacio, C Villanueva, ...
The Journal of clinical investigation 111 (1), 43-50, 2003
Inhibition of tumor angiogenesis by cannabinoids
C Blázquez, ML Casanova, A Planas, T Gómez del Pulgar, C Villanueva, ...
The FASEB journal 17 (3), 1-16, 2003
Design, synthesis and pharmacology of cannabimimetic indoles
JW Huffman, D Dai, BR Martin, DR Compton
Bioorganic & Medicinal Chemistry Letters 4 (4), 563-566, 1994
Structure–activity relationships for 1-alkyl-3-(1-naphthoyl) indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New …
JW Huffman, G Zengin, MJ Wu, J Lu, G Hynd, K Bushell, ALS Thompson, ...
Bioorganic & medicinal chemistry 13 (1), 89-112, 2005
Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding
MM Aung, G Griffin, JW Huffman, MJ Wu, C Keel, B Yang, VM Showalter, ...
Drug and alcohol dependence 60 (2), 133-140, 2000
3-(1′, 1′-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor
JW Huffman, J Liddle, S Yu, MM Aung, ME Abood, JL Wiley, BR Martin
Bioorganic & medicinal chemistry 7 (12), 2905-2914, 1999
JWH018, a common constituent of ‘Spice’ herbal blends, is a potent and efficacious cannabinoid CB1 receptor agonist
BK Atwood, J Huffman, A Straiker, K Mackie
British journal of pharmacology 160 (3), 585-593, 2010
Structure-activity relationships of indole-and pyrrole-derived cannabinoids
JL Wiley, DR Compton, D Dai, JAH Lainton, M Phillips, JW Huffman, ...
Journal of Pharmacology and Experimental Therapeutics 285 (3), 995-1004, 1998
Cannabinoid‐2 receptor mediates protection against hepatic ischemia/reperfusion injury
S Bátkai, D Osei‐Hyiaman, H Pan, O El‐Assal, M Rajesh, ...
The FASEB Journal 21 (8), 1788-1800, 2007
CB2-receptor stimulation attenuates TNF-α-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion
M Rajesh, P Mukhopadhyay, S Bátkai, G Hasko, L Liaudet, JW Huffman, ...
American Journal of Physiology-Heart and Circulatory Physiology 293 (4 …, 2007
Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes
JW Huffman, LW Padgett
Current medicinal chemistry 12 (12), 1395-1411, 2005
Evidence for the presence of CB2-like cannabinoid receptors on peripheral nerve terminals
G Griffin, SR Fernando, RA Ross, NG McKay, MLJ Ashford, D Shire, ...
European journal of pharmacology 339 (1), 53-61, 1997
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor
JW Huffman, S Yu, V Showalter, ME Abood, JL Wiley, DR Compton, ...
Journal of medicinal chemistry 39 (20), 3875-3877, 1996
1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles
JW Huffman, PV Szklennik, A Almond, K Bushell, DE Selley, H He, ...
Bioorganic & Medicinal Chemistry Letters 15 (18), 4110-4113, 2005
3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor
JW Huffman, R Mabon, MJ Wu, J Lu, R Hart, DP Hurst, PH Reggio, ...
Bioorganic & medicinal chemistry 11 (4), 539-549, 2003
Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids
JL Wiley, JA Marusich, JW Huffman
Life sciences 97 (1), 55-63, 2014
Cannabimimetic indoles, pyrroles and indenes
JW Huffman
Current medicinal chemistry 6, 705-720, 1999
CB2 cannabinoid receptor agonists attenuate TNF‐α‐induced human vascular smooth muscle cell proliferation and migration
M Rajesh, P Mukhopadhyay, G Hasko, JW Huffman, K Mackie, P Pacher
British journal of pharmacology 153 (2), 347-357, 2008
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