Frank Bosmans
Frank Bosmans
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TitleCited byYear
Deconstructing voltage sensor function and pharmacology in sodium channels
F Bosmans, MF Martin-Eauclaire, KJ Swartz
Nature 456 (7219), 202, 2008
Voltage-gated sodium channel modulation by scorpion α-toxins
F Bosmans, J Tytgat
Toxicon 49 (2), 142-158, 2007
Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes
F Bosmans, L Rash, S Zhu, S Diochot, M Lazdunski, P Escoubas, J Tytgat
Molecular pharmacology 69 (2), 419-429, 2006
Interactions between lipids and voltage sensor paddles detected with tarantula toxins
M Milescu, F Bosmans, S Lee, ARA Alabi, JI Kim, KJ Swartz
Nature structural & molecular biology 16 (10), 1080, 2009
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
JD Osteen, V Herzig, J Gilchrist, JJ Emrick, C Zhang, X Wang, J Castro, ...
Nature 534 (7608), 494, 2016
The hitchhiker’s guide to the voltage-gated sodium channel galaxy
CA Ahern, J Payandeh, F Bosmans, B Chanda
The Journal of general physiology 147 (1), 1-24, 2016
Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels
F Bosmans, J Tytgat
Toxicon 49 (4), 550-560, 2007
Targeting voltage sensors in sodium channels with spider toxins
F Bosmans, KJ Swartz
Trends in pharmacological sciences 31 (4), 175-182, 2010
From foe to friend: using animal toxins to investigate ion channel function
J Kalia, M Milescu, J Salvatierra, J Wagner, JK Klint, GF King, BM Olivera, ...
Journal of molecular biology 427 (1), 158-175, 2015
Function and solution structure of hainantoxin‐I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana1
D Li, Y Xiao, W Hu, J Xie, F Bosmans, J Tytgat, S Liang
FEBS letters 555 (3), 616-622, 2003
Animal peptides targeting voltage-activated sodium channels
B Billen, F Bosmans, J Tytgat
Current pharmaceutical design 14 (24), 2492-2502, 2008
Adaptive evolution of scorpion sodium channel toxins
S Zhu, F Bosmans, J Tytgat
Journal of molecular evolution 58 (2), 145-153, 2004
Crystallographic insights into sodium-channel modulation by the β4 subunit
J Gilchrist, S Das, F Van Petegem, F Bosmans
Proceedings of the National Academy of Sciences 110 (51), E5016-E5024, 2013
Importance of the Conserved Aromatic Residues in the Scorpion α-Like Toxin BmK M1 THE HYDROPHOBIC SURFACE REGION REVISITED
YM Sun, F Bosmans, RH Zhu, C Goudet, YM Xiong, J Tytgat, DC Wang
Journal of Biological Chemistry 278 (26), 24125-24131, 2003
Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a
JR Deuis, Z Dekan, JS Wingerd, JJ Smith, NR Munasinghe, RF Bhola, ...
Scientific reports 7, 40883, 2017
The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect‐selective toxins
F Bosmans, A Aneiros, J Tytgat
FEBS letters 532 (1-2), 131-134, 2002
Seven novel modulators of the analgesic target NaV1.7 uncovered using a high‐throughput venom‐based discovery approach
JK Klint, JJ Smith, I Vetter, DB Rupasinghe, SY Er, S Senff, V Herzig, ...
British journal of pharmacology 172 (10), 2445-2458, 2015
OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage‐gated Na+ channels
A Jalali, F Bosmans, M Amininasab, E Clynen, E Cuypers, ...
FEBS letters 579 (19), 4181-4186, 2005
Molecular basis of the mammalian potency of the scorpion α-like toxin, BmK M1
LH Liu, F Bosmans, C Maertens, RH Zhu, DC Wang, J Tytgat
The FASEB journal 19 (6), 594-596, 2005
A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a
NS Bende, S Dziemborowicz, M Mobli, V Herzig, J Gilchrist, J Wagner, ...
Nature communications 5, 4350, 2014
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