ABCF ATPases involved in protein synthesis, ribosome assembly and antibiotic resistance: structural and functional diversification across the tree of life V Murina, M Kasari, H Takada, M Hinnu, CK Saha, JW Grimshaw, T Seki, ... Journal of molecular biology 431 (18), 3568-3590, 2019 | 109 | 2019 |
Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases E Enkvist, D Lavogina, G Raidaru, A Vaasa, I Viil, M Lust, K Viht, A Uri Journal of medicinal chemistry 49 (24), 7150-7159, 2006 | 82 | 2006 |
Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest V Murina, M Kasari, V Hauryliuk, GC Atkinson Nucleic acids research 46 (7), 3753-3763, 2018 | 69 | 2018 |
Protein-induced long lifetime luminescence of nonmetal probes E Enkvist, A Vaasa, M Kasari, M Kriisa, T Ivan, K Ligi, G Raidaru, A Uri ACS chemical biology 6 (10), 1052-1062, 2011 | 54 | 2011 |
Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein … D Lavogina, M Lust, I Viil, N Konig, G Raidaru, J Rogozina, E Enkvist, ... Journal of medicinal chemistry 52 (2), 308-321, 2009 | 54 | 2009 |
Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP-and protein-competitive ligands of cAMP … K Viht, S Schweinsberg, M Lust, A Vaasa, G Raidaru, D Lavogina, A Uri, ... Analytical biochemistry 362 (2), 268-277, 2007 | 49 | 2007 |
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens C Crowe-McAuliffe, V Murina, KJ Turnbull, M Kasari, M Mohamad, C Polte, ... Nature Communications 12 (1), 3577, 2021 | 42 | 2021 |
Small-molecule FRET probes for protein kinase activity monitoring in living cells A Vaasa, M Lust, A Terrin, A Uri, M Zaccolo Biochemical and biophysical research communications 397 (4), 750-755, 2010 | 37 | 2010 |
Time-gated luminescence assay using nonmetal probes for determination of protein kinase activity-based disease markers M Kasari, P Padrik, A Vaasa, K Saar, K Leppik, J Soplepmann, A Uri Analytical biochemistry 422 (2), 79-88, 2012 | 32 | 2012 |
Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics C Crowe-McAuliffe, V Murina, KJ Turnbull, S Huch, M Kasari, H Takada, ... Nature Communications 13 (1), 1860, 2022 | 28 | 2022 |
Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases R Ekambaram, E Enkvist, G babu Manoharan, M Ugandi, M Kasari, K Viht, ... Chemical communications 50 (31), 4096-4098, 2014 | 25 | 2014 |
Bisubstrate fluorescent probes and biosensors in binding assays for HTS of protein kinase inhibitors A Uri, M Lust, A Vaasa, D Lavogina, K Viht, E Enkvist Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 541-546, 2010 | 25 | 2010 |
Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors M Kasari, K Ligi, JAG Williams, A Vaasa, E Enkvist, K Viht, LO Pålsson, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1330-1335, 2013 | 24 | 2013 |
Selective Bisubstrate Inhibitors with Sub‐nanomolar Affinity for Protein Kinase Pim‐1 R Ekambaram, E Enkvist, A Vaasa, M Kasari, G Raidaru, S Knapp, A Uri ChemMedChem 8 (6), 909-913, 2013 | 24 | 2013 |
Adenosine–oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton H Räägel, M Lust, A Uri, M Pooga The FEBS Journal 275 (14), 3608-3624, 2008 | 22 | 2008 |
Conjugates of 5-isoquinolinesulfonylamides and oligo-D-arginine possess high affinity and selectivity towards Rho kinase (ROCK) D Lavogina, K Kalind, J Bredihhina, M Hurt, A Vaasa, M Kasari, E Enkvist, ... Bioorganic & medicinal chemistry letters 22 (10), 3425-3430, 2012 | 20 | 2012 |
Adenosine analogue–oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIα) D Lavogina, CK Nickl, E Enkvist, G Raidaru, M Lust, A Vaasa, A Uri, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (9), 1857-1868, 2010 | 15 | 2010 |
FRET-based screening assay using small-molecule photoluminescent probes in lysate of cells overexpressing RFP-fused protein kinases G babu Manoharan, E Enkvist, M Kasari, K Viht, M Zenn, A Prinz, O Filhol, ... Analytical biochemistry 481, 10-17, 2015 | 13 | 2015 |
Decoupling growth and production by removing the origin of replication from a bacterial chromosome M Kasari, V Kasari, M Kärmas, A Jõers ACS Synthetic Biology 11 (8), 2610-2622, 2022 | 11 | 2022 |
Designed whole-cell-catalysis-assisted synthesis of 9, 11-secosterols M Kõllo, M Kasari, V Kasari, T Pehk, I Järving, M Lopp, A Jõers, T Kanger Beilstein Journal of Organic Chemistry 17 (1), 581-588, 2021 | 7 | 2021 |