Rui Moreira
Rui Moreira
Faculty of Pharmacy, University of Lisbon
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Cited by
Cited by
Towards the sustainable discovery and development of new antibiotics
M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ...
Nature Reviews Chemistry 5 (10), 726-749, 2021
Primaquine revisited six decades after its discovery
N Vale, R Moreira, P Gomes
European journal of medicinal chemistry 44 (3), 937-953, 2009
Synthetic organic chemistry driven by artificial intelligence
AF de Almeida, R Moreira, T Rodrigues
Nature Reviews Chemistry 3 (10), 589-604, 2019
Indoloquinolines as scaffolds for drug discovery
J Lavrado, R Moreira, A Paulo
Current medicinal chemistry 17 (22), 2348-2370, 2010
Michael acceptors as cysteine protease inhibitors.
MM Santos, R Moreira
Mini reviews in medicinal chemistry 7 (10), 1040-1050, 2007
Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho [2, 3-d] isoxazole-4, 9-diones
MMM Santos, N Faria, J Iley, SJ Coles, MB Hursthouse, ML Martins, ...
Bioorganic & medicinal chemistry letters 20 (1), 193-195, 2010
Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
FP da Cruz, C Martin, K Buchholz, MJ Lafuente-Monasterio, T Rodrigues, ...
Journal of Infectious Diseases 205 (8), 1278-1286, 2012
An overview of drug resistance in protozoal diseases
R Capela, R Moreira, F Lopes
International journal of molecular sciences 20 (22), 5748, 2019
Drug discovery in tuberculosis. New drug targets and antimycobacterial agents
A Campaniço, R Moreira, F Lopes
European journal of medicinal chemistry 150, 525-545, 2018
Design of Modular G‐quadruplex Ligands
AR Duarte, E Cadoni, AS Ressurreição, R Moreira, A Paulo
ChemMedChem 13 (9), 869-893, 2018
Targeting COPD: advances on low‐molecular‐weight inhibitors of human neutrophil elastase
SD Lucas, E Costa, RC Guedes, R Moreira
Medicinal research reviews 33 (S1), E73-E101, 2013
Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials
MJ Araújo, J Bom, R Capela, C Casimiro, P Chambel, P Gomes, J Iley, ...
Journal of medicinal chemistry 48 (3), 888-892, 2005
Targeting the liver stage of malaria parasites: a yet unmet goal
T Rodrigues, M Prudêncio, R Moreira, MM Mota, F Lopes
Journal of medicinal chemistry 55 (3), 995-1012, 2012
Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins
KK Hanson, AS Ressurreição, K Buchholz, M Prudêncio, ...
Proceedings of the National Academy of Sciences 110 (30), E2838-E2847, 2013
Metabolism of primaquine by liver homogenate fractions: evidence for monoamine oxidase and cytochrome P450 involvement in the oxidative deamination of primaquine to …
L Constantino, P Paixao, R Moreira, MJ Portela, VE Do Rosario, J Iley
Experimental and Toxicologic Pathology 51 (4-5), 299-303, 1999
KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines
J Lavrado, H Brito, PM Borralho, SA Ohnmacht, NS Kim, C Leitão, S Pisco, ...
Scientific reports 5 (1), 9696, 2015
Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy
R Capela, GG Cabal, PJ Rosenthal, J Gut, MM Mota, R Moreira, F Lopes, ...
Antimicrobial agents and chemotherapy 55 (10), 4698-4706, 2011
Synthesis of imidazolidin-4-one and 1H-imidazo [2, 1-a] isoindole-2, 5 (3H, 9bH)-dione derivatives of primaquine: scope and limitations
P Gomes, MJ Araújo, M Rodrigues, N Vale, Z Azevedo, J Iley, P Chambel, ...
Tetrahedron 60 (26), 5551-5562, 2004
Cyclization-activated prodrugs
P Gomes, N Vale, R Moreira
Molecules 12 (11), 2484-2506, 2007
Amidomethylation of amodiaquine: antimalarial N-Mannich base derivatives
F Lopes, R Capela, JO Gonçaves, PN Horton, MB Hursthouse, J Iley, ...
Tetrahedron letters 45 (41), 7663-7666, 2004
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