Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1 YF Wang, CC Jiang, KA Kiejda, S Gillespie, XD Zhang, P Hersey Clinical cancer research 13 (16), 4934-4942, 2007 | 223 | 2007 |
Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value C Stirzaker, E Zotenko, JZ Song, W Qu, SS Nair, WJ Locke, A Stone, ... Nature communications 6 (1), 1-11, 2015 | 216 | 2015 |
Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress CC Jiang, K Lucas, KA Avery-Kiejda, M Wade, CE debock, RF Thorne, ... Cancer Research 68 (16), 6708-6717, 2008 | 176 | 2008 |
Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis CC Jiang, LH Chen, S Gillespie, YF Wang, KA Kiejda, XD Zhang, ... Cancer research 67 (20), 9750-9761, 2007 | 162 | 2007 |
Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin KA Avery-Kiejda, XD Zhang, LJ Adams, RJ Scott, B Vojtesek, DP Lane, ... Clinical Cancer Research 14 (6), 1659-1668, 2008 | 152 | 2008 |
BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer MW Wong, C Nordfors, D Mossman, G Pecenpetelovska, KA Avery-Kiejda, ... Breast cancer research and treatment 127 (3), 853-859, 2011 | 137 | 2011 |
Tunicamycin sensitizes human melanoma cells to tumor necrosis factor–related apoptosis-inducing ligand–induced apoptosis by up-regulation of trail-r2 via the unfolded protein … CC Jiang, LH Chen, S Gillespie, KA Kiejda, N Mhaidat, YF Wang, ... Cancer research 67 (12), 5880-5888, 2007 | 136 | 2007 |
Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A. PA Mote, JA Leary, KA Avery, K Sandelin, G Chenevix-Trench, JA Kirk, ... Genes Chromosomes Cancer 39, 236-48, 2004 | 127 | 2004 |
P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation KA Avery-Kiejda, NA Bowden, AJ Croft, LL Scurr, CF Kairupan, KA Ashton, ... BMC cancer 11 (1), 203, 2011 | 125 | 2011 |
Docetaxel-induced apoptosis in melanoma cells is dependent on activation of caspase-2 NM Mhaidat, Y Wang, KA Kiejda, XD Zhang, P Hersey Molecular Cancer Therapeutics 6 (2), 752-761, 2007 | 118 | 2007 |
Decreased expression of key tumour suppressor microRNAs is associated with lymph node metastases in triple negative breast cancer KA Avery-Kiejda, SG Braye, A Mathe, JF Forbes, RJ Scott BMC cancer 14 (1), 51, 2014 | 115 | 2014 |
The relative mRNA expression of p53 isoforms in breast cancer is associated with clinical features and outcome KA Avery-Kiejda, B Morten, MW Wong-Brown, A Mathe, RJ Scott Carcinogenesis 35 (3), 586-596, 2013 | 109 | 2013 |
Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells CC Jiang, ZG Mao, KA Avery-Kiejda, M Wade, P Hersey, XD Zhang Carcinogenesis 30 (2), 197-204, 2008 | 102 | 2008 |
MiRNAs and other epigenetic changes as biomarkers in triple negative breast cancer A Mathe, RJ Scott, KA Avery-Kiejda International journal of molecular sciences 16 (12), 28347-28376, 2015 | 97 | 2015 |
Temozolomide induces senescence but not apoptosis in human melanoma cells NM Mhaidat, XD Zhang, J Allen, KA Avery-Kiejda, RJ Scott, P Hersey British journal of cancer 97 (9), 1225-1233, 2007 | 94 | 2007 |
The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer KA Avery-Kiejda, SG Braye, JF Forbes, RJ Scott BMC cancer 14 (1), 253, 2014 | 78 | 2014 |
Proteotranscriptomic profiling of 231-BR breast cancer cells: identification of potential biomarkers and therapeutic targets for brain metastasis MD Dun, RJ Chalkley, S Faulkner, S Keene, KA Avery-Kiejda, RJ Scott, ... Molecular & Cellular Proteomics 14 (9), 2316-2330, 2015 | 76 | 2015 |
Inhibition of endoplasmic reticulum stress–induced apoptosis of melanoma cells by the ARC protein LH Chen, CC Jiang, R Watts, RF Thorne, KA Kiejda, XD Zhang, P Hersey Cancer research 68 (3), 834-842, 2008 | 64 | 2008 |
Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response LH Chen, CC Jiang, KA Kiejda, YF Wang, RF Thorne, XD Zhang, ... Carcinogenesis 28 (11), 2328-2336, 2007 | 61 | 2007 |
Novel genes associated with lymph node metastasis in triple negative breast cancer A Mathe, M Wong-Brown, B Morten, JF Forbes, SG Braye, ... Scientific reports 5, 15832, 2015 | 57 | 2015 |