Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells P Artursson, J Karlsson Biochemical and biophysical research communications 175 (3), 880-885, 1991 | 2063 | 1991 |
Caco-2 monolayers in experimental and theoretical predictions of drug transport P Artursson, K Palm, K Luthman Advanced drug delivery reviews 46 (1-3), 27-43, 2001 | 1334 | 2001 |
Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorbtive (Caco‐2) cells PER Artursson Journal of pharmaceutical sciences 79 (6), 476-482, 1990 | 1019 | 1990 |
Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers I Hubatsch, EGE Ragnarsson, P Artursson Nature protocols 2 (9), 2111, 2007 | 915 | 2007 |
Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2) P Artursson, T Lindmark, SS Davis, L Illum Pharmaceutical research 11 (9), 1358-1361, 1994 | 914 | 1994 |
Polar molecular surface properties predict the intestinal absorption of drugs in humans K Palm, P Stenberg, K Luthman, P Artursson Pharmaceutical research 14 (5), 568-571, 1997 | 792 | 1997 |
Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement NGM Schipper, S Olsson, JA Hoogstraate, AG deBoer, KM Vårum, ... Pharmaceutical research 14 (7), 923-929, 1997 | 708 | 1997 |
Chitosan as a nonviral gene delivery system. Structure–property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo M Köping-Höggård, I Tubulekas, H Guan, K Edwards, M Nilsson, ... Gene therapy 8 (14), 1108-1121, 2001 | 617 | 2001 |
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines C Hilgendorf, G Ahlin, A Seithel, P Artursson, AL Ungell, J Karlsson Drug Metabolism and Disposition 35 (8), 1333-1340, 2007 | 570 | 2007 |
Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell … J Taipalensuu, H Törnblom, G Lindberg, C Einarsson, F Sjöqvist, ... Journal of Pharmacology and Experimental Therapeutics 299 (1), 164-170, 2001 | 541 | 2001 |
Coexistence of passive and carrier-mediated processes in drug transport K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ... Nature reviews Drug discovery 9 (8), 597-614, 2010 | 491 | 2010 |
Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial … NGM Schipper, KM Vårum, P Artursson Pharmaceutical research 13 (11), 1686-1692, 1996 | 480 | 1996 |
Correlation of drug absorption with molecular surface properties K Palm, K Luthman, AL Unge, G Strandlund, P Artursson Journal of pharmaceutical sciences 85 (1), 32-39, 1996 | 449 | 1996 |
Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers M Köping-Höggård, KM Vårum, M Issa, S Danielsen, BE Christensen, ... Gene therapy 11 (19), 1441-1452, 2004 | 430 | 2004 |
Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in Caco-2 cells T Lindmark, Y Kimura, P Artursson Journal of Pharmacology and Experimental Therapeutics 284 (1), 362-369, 1998 | 384 | 1998 |
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool H Gad, T Koolmeister, AS Jemth, S Eshtad, SA Jacques, CE Ström, ... Nature 508 (7495), 215-221, 2014 | 377 | 2014 |
Caco-2 monolayers in experimental and theoretical predictions of drug transport P Artursson, K Palm, K Luthman Advanced drug delivery reviews 22 (1-2), 67-84, 1996 | 366 | 1996 |
Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond P Artursson, RT Borchardt Pharmaceutical research 14 (12), 1655, 1997 | 361 | 1997 |
Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with Caco-2 cells G Englund, F Rorsman, A Rönnblom, U Karlbom, L Lazorova, J Gråsjö, ... European Journal of Pharmaceutical Sciences 29 (3-4), 269-277, 2006 | 360 | 2006 |
Cell cultures as models for drug absorption across the intestinal mucosa. P Artursson Critical reviews in therapeutic drug carrier systems 8 (4), 305-330, 1991 | 337 | 1991 |