The non-protein amino acid BMAA is misincorporated into human proteins in place of L-serine causing protein misfolding and aggregation RA Dunlop, PA Cox, SA Banack, KJ Rodgers PloS one 8 (9), e75376, 2013 | 282 | 2013 |
Oxidized proteins: mechanisms of removal and consequences of accumulation RA Dunlop, UT Brunk, KJ Rodgers IUBMB life 61 (5), 522-527, 2009 | 156 | 2009 |
Recent developments in the intracellular degradation of oxidized proteins RA Dunlop, KJ Rodgers, RT Dean Free Radical Biology and Medicine 33 (7), 894-906, 2002 | 103 | 2002 |
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols J Zeng, RA Dunlop, KJ Rodgers, MJ Davies Biochemical Journal 398 (2), 197-206, 2006 | 90 | 2006 |
Revisiting adverse reactions to vaccines: A critical appraisal of Autoimmune Syndrome Induced by Adjuvants (ASIA) D Hawkes, J Benhamu, T Sidwell, R Miles, RA Dunlop Journal of Autoimmunity 59, 77-84, 2015 | 56 | 2015 |
The impact of specific oxidized amino acids on protein turnover in J774 cells RA Dunlop, RT Dean, KJ Rodgers Biochemical Journal 410 (1), 131-140, 2008 | 49 | 2008 |
L-serine: a naturally-occurring amino acid with therapeutic potential JS Metcalf, RA Dunlop, JT Powell, SA Banack, PA Cox Neurotoxicity research 33 (1), 213-221, 2018 | 47 | 2018 |
L-DOPA is incorporated into brain proteins of patients treated for Parkinson's disease, inducing toxicity in human neuroblastoma cells in vitro SW Chan, RA Dunlop, A Rowe, KL Double, KJ Rodgers Experimental Neurology 238 (1), 29-37, 2012 | 43 | 2012 |
Biosynthesis and turnover of DOPA-containing proteins by human cells KJ Rodgers, PM Hume, RA Dunlop, RT Dean Free Radical Biology and Medicine 37 (11), 1756-1764, 2004 | 43 | 2004 |
An miRNA fingerprint using neural-enriched extracellular vesicles from blood plasma: towards a biomarker for amyotrophic lateral sclerosis/motor neuron disease SA Banack, RA Dunlop, PA Cox Open biology 10 (6), 200116, 2020 | 30 | 2020 |
Proteins containing oxidized amino acids induce apoptosis in human monocytes RA Dunlop, UT Brunk, KJ Rodgers Biochemical Journal 435 (1), 207-216, 2011 | 29 | 2011 |
The use of L-serine to prevent β-methylamino-L-alanine (BMAA)-induced proteotoxic stress in vitro BJ Main, RA Dunlop, KJ Rodgers Toxicon 109, 7-12, 2016 | 28 | 2016 |
L-serine-mediated neuroprotection includes the upregulation of the ER stress chaperone protein disulfide isomerase (PDI) RA Dunlop, JT Powell, JS Metcalf, GJ Guillemin, PA Cox Neurotoxicity Research 33 (1), 113-122, 2018 | 25 | 2018 |
Kavalactones Yangonin and Methysticin Induce Apoptosis in Human Hepatocytes (HepG2) In Vitro J Tang, RA Dunlop, A Rowe, KJ Rodgers, I Ramzan Phytotherapy Research 25 (3), 417-423, 2011 | 23 | 2011 |
Oxidative bioactivation of crotyl alcohol to the toxic endogenous aldehyde crotonaldehyde: association of protein carbonylation with toxicity in mouse hepatocytes FR Fontaine, RA Dunlop, DR Petersen, PC Burcham Chemical research in toxicology 15 (8), 1051-1058, 2002 | 22 | 2002 |
The cyanobacteria-derived BMAA can be incorporated into cell proteins and could thus be an environmental trigger for ALS and other neurological diseases associated with protein … K Rodgers Amyotrph. Lateral Sclero. 12 (1), 22, 2011 | 19 | 2011 |
Is exposure to BMAA a risk factor for neurodegenerative diseases? A response to a critical review of the BMAA hypothesis D Ra, B Sa, B Sl, M Js, M Sj, D DA, S Ew, B EB, C AD, G GG, C PA, M DC, ... Neurotoxicity research 39 (1), 81-106, 2021 | 16 | 2021 |
The cyanotoxin and non-protein amino acid β-methylamino-L-alanine (L-BMAA) in the food chain: incorporation into proteins and its impact on human health RA Dunlop, GJ Guillemin Neurotoxicity research 36 (3), 602-611, 2019 | 16 | 2019 |
Proteolytic'defences' and the accumulation of oxidized polypeptides in cataractogenesis and atherogenesis J Saklatvala, H Nagase, G Salvesen, RT Dean, R Dunlop, P Hume, ... Biochemical Society Symposia 70, 135-146, 2003 | 16 | 2003 |
The deleterious effects of non-protein amino acids from desert plants on human and animal health RA Dunlop, BJ Main, KJ Rodgers Journal of Arid Environments 112, 152-158, 2015 | 13 | 2015 |