Edze Westra
Edze Westra
Professor of Microbiology, University of Exeter, Biosciences, ESI
Verified email at exeter.ac.uk
Title
Cited by
Cited by
Year
Unravelling the structural and mechanistic basis of CRISPR–Cas systems
J Van Der Oost, ER Westra, RN Jackson, B Wiedenheft
Nature Reviews Microbiology 12 (7), 479-492, 2014
77762014
Small CRISPR RNAs guide antiviral defense in prokaryotes
SJJ Brouns, MM Jore, M Lundgren, ER Westra, RJH Slijkhuis, ...
Science 321 (5891), 960-964, 2008
23192008
Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
E Semenova, MM Jore, KA Datsenko, A Semenova, ER Westra, B Wanner, ...
Proceedings of the National Academy of Sciences 108 (25), 10098-10103, 2011
7572011
CRISPR-based adaptive and heritable immunity in prokaryotes
J Van der Oost, MM Jore, ER Westra, M Lundgren, SJJ Brouns
Trends in biochemical sciences 34 (8), 401-407, 2009
5572009
Structural basis for CRISPR RNA-guided DNA recognition by Cascade
MM Jore, M Lundgren, E Van Duijn, JB Bultema, ER Westra, ...
Nature structural & molecular biology 18 (5), 529, 2011
5442011
CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3
ER Westra, PBG van Erp, T KŁnne, SP Wong, RHJ Staals, CLC Seegers, ...
Molecular cell 46 (5), 595-605, 2012
5432012
The CRISPRs, They Are A-Changin': How Prokaryotes Generate Adaptive Immunity
ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost
Annual Reviews of Genetics 46 (1), 311, 2012
3252012
DNA-guided DNA interference by a prokaryotic Argonaute
DC Swarts, MM Jore, ER Westra, Y Zhu, JH Janssen, AP Snijders, ...
Nature 507 (7491), 258-261, 2014
2702014
CRISPR–Cas systems: beyond adaptive immunity
ER Westra, A Buckling, PC Fineran
Nature reviews Microbiology 12 (5), 317-326, 2014
2612014
H‐NS‐mediated repression of CRISPR‐based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO
ER Westra, ‹ Pul, N Heidrich, MM Jore, M Lundgren, T Stratmann, ...
Molecular microbiology 77 (6), 1380-1393, 2010
2322010
Crystal structure of the CRISPR RNA–guided surveillance complex from Escherichia coli
RN Jackson, SM Golden, PBG van Erp, J Carter, ER Westra, SJJ Brouns, ...
Science 345 (6203), 1473-1479, 2014
2282014
Type IE CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition
ER Westra, E Semenova, KA Datsenko, RN Jackson, B Wiedenheft, ...
PLoS Genet 9 (9), e1003742, 2013
1952013
Parasite exposure drives selective evolution of constitutive versus inducible defense
ER Westra, S van Houte, S Oyesiku-Blakemore, B Makin, JM Broniewski, ...
Current biology 25 (8), 1043-1049, 2015
1682015
Clustered regularly interspaced short palindromic repeats (CRISPRs): the hallmark of an ingenious antiviral defense mechanism in prokaryotes
S Al-Attar, ER Westra, J Van Der Oost, SJJ Brouns
Walter de Gruyter 392 (4), 277-289, 2011
1672011
The diversity-generating benefits of a prokaryotic adaptive immune system
S van Houte, AKE Ekroth, JM Broniewski, H Chabas, B Ashby, ...
Nature 532 (7599), 385-388, 2016
1662016
Prophages mediate defense against phage infection through diverse mechanisms
J Bondy-Denomy, J Qian, ER Westra, A Buckling, DS Guttman, ...
The ISME journal 10 (12), 2854-2866, 2016
1542016
Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system
NM HÝyland-Kroghsbo, J Paczkowski, S Mukherjee, J Broniewski, ...
Proceedings of the National Academy of Sciences 114 (1), 131-135, 2017
1332017
Evolutionary ecology of prokaryotic immune mechanisms
S van Houte, A Buckling, ER Westra
Microbiology and Molecular Biology Reviews 80 (3), 745-763, 2016
1152016
Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex
TR Blosser, L Loeff, ER Westra, M Vlot, T KŁnne, M Sobota, C Dekker, ...
Molecular cell 58 (1), 60-70, 2015
992015
Anti-CRISPR phages cooperate to overcome CRISPR-Cas immunity
M Landsberger, S Gandon, S Meaden, C Rollie, A Chevallereau, ...
Cell 174 (4), 908-916. e12, 2018
972018
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