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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells J Utikal, JM Polo, M Stadtfeld, N Maherali, W Kulalert, RM Walsh, A Khalil, ... Nature 460 (7259), 1145-1148, 2009 | 1070 | 2009 |
A molecular roadmap of reprogramming somatic cells into iPS cells JM Polo, E Anderssen, RM Walsh, BA Schwarz, CM Nefzger, SM Lim, ... Cell 151 (7), 1617-1632, 2012 | 1016 | 2012 |
Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice K Arnold, A Sarkar, MA Yram, JM Polo, R Bronson, S Sengupta, ... Cell stem cell 9 (4), 317-329, 2011 | 869 | 2011 |
A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation A Grubman, G Chew, JF Ouyang, G Sun, XY Choo, C McLean, ... Nature neuroscience 22 (12), 2087-2097, 2019 | 766 | 2019 |
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells Y Ohi, H Qin, C Hong, L Blouin, JM Polo, T Guo, Z Qi, SL Downey, ... Nature cell biology 13 (5), 541-549, 2011 | 690 | 2011 |
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes E Mariño, JL Richards, KH McLeod, D Stanley, YA Yap, J Knight, ... Nature immunology 18 (5), 552-562, 2017 | 685 | 2017 |
Class-switch recombination occurs infrequently in germinal centers JA Roco, L Mesin, SC Binder, C Nefzger, P Gonzalez-Figueroa, ... Immunity 51 (2), 337-350. e7, 2019 | 545 | 2019 |
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells JM Polo, T Dell'Oso, SM Ranuncolo, L Cerchietti, D Beck, GF Da Silva, ... Nature medicine 10 (12), 1329-1335, 2004 | 355 | 2004 |
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo LC Cerchietti, AF Ghetu, X Zhu, GF Da Silva, S Zhong, M Matthews, ... Cancer cell 17 (4), 400-411, 2010 | 354 | 2010 |
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR SM Ranuncolo, JM Polo, J Dierov, M Singer, T Kuo, J Greally, R Green, ... Nature immunology 8 (7), 705-714, 2007 | 347 | 2007 |
A predictive computational framework for direct reprogramming between human cell types OJL Rackham, J Firas, H Fang, ME Oates, ML Holmes, AS Knaupp, ... Nature genetics 48 (3), 331-335, 2016 | 314 | 2016 |
Modelling human blastocysts by reprogramming fibroblasts into iBlastoids X Liu, JP Tan, J Schröder, A Aberkane, JF Ouyang, M Mohenska, SM Lim, ... Nature 591 (7851), 627-632, 2021 | 308 | 2021 |
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency J Hansson, MR Rafiee, S Reiland, JM Polo, J Gehring, S Okawa, W Huber, ... Cell reports 2 (6), 1579-1592, 2012 | 283 | 2012 |
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL W Ci, JM Polo, L Cerchietti, R Shaknovich, L Wang, SN Yang, K Ye, ... Blood, The Journal of the American Society of Hematology 113 (22), 5536-5548, 2009 | 278 | 2009 |
A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells C Buecker, HH Chen, JM Polo, L Daheron, L Bu, TS Barakat, P Okwieka, ... Cell stem cell 6 (6), 535-546, 2010 | 274 | 2010 |
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming E Apostolou, F Ferrari, RM Walsh, O Bar-Nur, M Stadtfeld, S Cheloufi, ... Cell stem cell 12 (6), 699-712, 2013 | 229 | 2013 |
Transcriptional signature in microglia associated with Aβ plaque phagocytosis A Grubman, XY Choo, G Chew, JF Ouyang, G Sun, NP Croft, FJ Rossello, ... Nature communications 12 (1), 3015, 2021 | 217 | 2021 |
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo LC Cerchietti, SN Yang, R Shaknovich, K Hatzi, JM Polo, A Chadburn, ... Blood, The Journal of the American Society of Hematology 113 (15), 3397-3405, 2009 | 200 | 2009 |
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters K Hatzi, Y Jiang, C Huang, F Garrett-Bakelman, MD Gearhart, ... Cell reports 4 (3), 578-588, 2013 | 196 | 2013 |