| TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ SJ Pitt, TM Funnell, M Sitsapesan, E Venturi, K Rietdorf, M Ruas, ... Journal of Biological Chemistry 285 (45), 35039-35046, 2010 | 246 | 2010 |
| Reconstituted human TPC1 is a proton-permeable ion channel and is activated by NAADP or Ca2+ SJ Pitt, AKM Lam, K Rietdorf, A Galione, R Sitsapesan Science signaling 7 (326), ra46-ra46, 2014 | 98 | 2014 |
| Monitoring contractility in cardiac tissue with cellular resolution using biointegrated microlasers M Schubert, L Woolfson, IRM Barnard, AM Dorward, B Casement, ... Nature Photonics 14 (7), 452-458, 2020 | 96 | 2020 |
| FKBP12 Activates the Cardiac Ryanodine Receptor Ca2+-Release Channel and Is Antagonised by FKBP12.6 E Galfre, SJ Pitt, E Venturi, M Sitsapesan, NR Zaccai, ... PloS one 7 (2), e31956, 2012 | 78 | 2012 |
| Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release J Woodier, RD Rainbow, AJ Stewart, SJ Pitt Journal of Biological Chemistry 290 (28), 17599-17610, 2015 | 70 | 2015 |
| A family of Type VI secretion system effector proteins that form ion-selective pores G Mariano, K Trunk, DJ Williams, L Monlezun, H Strahl, SJ Pitt, ... Nature communications 10 (1), 5484, 2019 | 63 | 2019 |
| Glycosaminoglycan neutralization in coagulation control AIS Sobczak, SJ Pitt, AJ Stewart Arteriosclerosis, thrombosis, and vascular biology 38 (6), 1258-1270, 2018 | 61 | 2018 |
| High intracellular chloride slows the decay of glycinergic currents SJ Pitt, LG Sivilotti, M Beato Journal of Neuroscience 28 (45), 11454-11467, 2008 | 59 | 2008 |
| Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets C Kapsalis, B Wang, H El Mkami, SJ Pitt, JR Schnell, TK Smith, JD Lippiat, ... Nature Communications 10 (1), 4619, 2019 | 52 | 2019 |
| Charade of the SR K+-channel: two ion-channels, TRIC-A and TRIC-B, masquerade as a single K+-channel SJ Pitt, KH Park, M Nishi, T Urashima, S Aoki, D Yamazaki, J Ma, ... Biophysical journal 99 (2), 417-426, 2010 | 52 | 2010 |
| Lack of evidence for functional ADP-activated human P2X1 receptors supports a role for ATP during hemostasis and thrombosis C Vial, SJ Pitt, J Roberts, MG Rolf, MP Mahaut-Smith, RJ Evans Blood 102 (10), 3646-3651, 2003 | 51 | 2003 |
| Total plasma magnesium, zinc, copper and selenium concentrations in type-I and type-II diabetes AIS Sobczak, F Stefanowicz, SJ Pitt, RA Ajjan, AJ Stewart Biometals 32, 123-138, 2019 | 50 | 2019 |
| Exploring the biophysical evidence that mammalian two‐pore channels are NAADP‐activated calcium‐permeable channels SJ Pitt, B Reilly‐O'Donnell, R Sitsapesan The Journal of physiology 594 (15), 4171-4179, 2016 | 45 | 2016 |
| A high fat diet induces sex-specific differences in hepatic lipid metabolism and nitrite/nitrate in rats J Stanimirovic, M Obradovic, A Jovanovic, E Sudar-Milovanovic, ... Nitric Oxide 54, 51-59, 2016 | 37 | 2016 |
| TRIC-B channels display labile gating: evidence from the TRIC-A knockout mouse model E Venturi, A Matyjaszkiewicz, SJ Pitt, K Tsaneva-Atanasova, M Nishi, ... Pflügers Archiv-European Journal of Physiology 465, 1135-1148, 2013 | 35 | 2013 |
| In vivo effects of 17β-estradiol on cardiac Na+/K+-ATPase expression and activity in rat heart M Obradovic, AJ Stewart, SJ Pitt, M Labudovic-Borovic, E Sudar, ... Molecular and Cellular Endocrinology 388 (1-2), 58-68, 2014 | 33 | 2014 |
| FKBP12. 6 activates RyR1: investigating the amino acid residues critical for channel modulation E Venturi, E Galfré, F O’Brien, SJ Pitt, S Bellamy, RB Sessions, ... Biophysical journal 106 (4), 824-833, 2014 | 29 | 2014 |
| Mitsugumin 23 forms a massive bowl-shaped assembly and cation-conducting channel E Venturi, K Mio, M Nishi, T Ogura, T Moriya, SJ Pitt, K Okuda, S Kakizawa, ... Biochemistry 50 (13), 2623-2632, 2011 | 28 | 2011 |
| Ca2+-Dependent Phosphorylation of RyR2 Can Uncouple Channel Gating from Direct Cytosolic Ca2+ Regulation S Carter, SJ Pitt, J Colyer, R Sitsapesan The Journal of Membrane Biology 240, 21-33, 2011 | 27 | 2011 |
| Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage B Reilly-O'Donnell, GB Robertson, A Karumbi, C McIntyre, W Bal, M Nishi, ... Journal of Biological Chemistry 292 (32), 13361-13373, 2017 | 24 | 2017 |
