| TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity EM Creagh, LAJ O’Neill Trends in immunology 27 (8), 352-357, 2006 | 1006 | 2006 |
| Autophagy controls IL-1β secretion by targeting pro-IL-1β for degradation J Harris, M Hartman, C Roche, SG Zeng, A O'Shea, FA Sharp, EM Lambe, ... Journal of Biological Chemistry 286 (11), 9587-9597, 2011 | 905 | 2011 |
| Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome FA Sharp, D Ruane, B Claass, E Creagh, J Harris, P Malyala, M Singh, ... Proceedings of the National Academy of Sciences 106 (3), 870-875, 2009 | 650 | 2009 |
| Apoptosis‐associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl‐2 C Adrain, EM Creagh, SJ Martin The EMBO journal, 2001 | 616 | 2001 |
| Caspase‐activation pathways in apoptosis and immunity EM Creagh, H Conroy, SJ Martin Immunological reviews 193 (1), 10-21, 2003 | 527 | 2003 |
| Analysis of the composition, assembly kinetics and activity of native Apaf‐1 apoptosomes MM Hill, C Adrain, PJ Duriez, EM Creagh, SJ Martin The EMBO journal 23 (10), 2134-2145, 2004 | 497 | 2004 |
| The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis EC Lavelle, C Murphy, LAJ O'neill, EM Creagh Mucosal immunology 3 (1), 17-28, 2010 | 306 | 2010 |
| Heat shock proteins–modulators of apoptosis in tumour cells EM Creagh, D Sheehan, TG Cotter Leukemia 14 (7), 1161-1173, 2000 | 295 | 2000 |
| Caspases: cellular demolition experts EM Creagh, SJ Martin Biochemical Society Transactions 29 (6), 696-702, 2001 | 280 | 2001 |
| Heat shock protein 70 inhibits caspase-dependent and-independent apoptosis in Jurkat T cells EM Creagh, RJ Carmody, TG Cotter Experimental cell research 257 (1), 58-66, 2000 | 259 | 2000 |
| Caspase crosstalk: integration of apoptotic and innate immune signalling pathways EM Creagh Trends in immunology 35 (12), 631-640, 2014 | 205 | 2014 |
| Antioxidant-mediated inhibition of the heat shock response leads to apoptosis AM Gorman, B Heavey, E Creagh, TG Cotter, A Samali FEBS letters 445 (1), 98-102, 1999 | 186 | 1999 |
| CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-κB activation pathways L Bouchier-Hayes, H Conroy, H Egan, C Adrain, EM Creagh, ... Journal of Biological Chemistry 276 (47), 44069-44077, 2001 | 133 | 2001 |
| Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins EM Creagh, BM Murphy, PJ Duriez, CS Duckett, SJ Martin Journal of Biological Chemistry 279 (26), 26906-26914, 2004 | 123 | 2004 |
| Protective role for caspase-11 during acute experimental murine colitis K Oficjalska, M Raverdeau, G Aviello, SC Wade, A Hickey, KM Sheehan, ... The Journal of immunology 194 (3), 1252-1260, 2015 | 93 | 2015 |
| Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man C Adrain, EM Creagh, SP Cullen, SJ Martin Journal of Biological Chemistry 279 (35), 36923-36930, 2004 | 88 | 2004 |
| Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1β secretion CE Becker, EM Creagh, LAJ O'Neill Journal of biological chemistry 284 (50), 34531-34537, 2009 | 75 | 2009 |
| Selective protection by hsp 70 against cytotoxic drug‐, but not Fas‐induced T‐cell apoptosis CREAGH, COTTER Immunology 97 (1), 36-44, 1999 | 73 | 1999 |
| Caspase-11 promotes allergic airway inflammation Z Zasłona, E Flis, MM Wilk, RG Carroll, EM Palsson-McDermott, ... Nature Communications 11 (1), 1055, 2020 | 62 | 2020 |
| Altered expression of caspases-4 and-5 during inflammatory bowel disease and colorectal cancer: diagnostic and therapeutic potential B Flood, K Oficjalska, D Laukens, J Fay, A O'Grady, F Caiazza, Z Heetun, ... Clinical & Experimental Immunology 181 (1), 39-50, 2015 | 43 | 2015 |
