Frank K. Huynh
Frank K. Huynh
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The pancreatic β cell is a key site for mediating the effects of leptin on glucose homeostasis
SD Covey, RD Wideman, C McDonald, S Unniappan, F Huynh, A Asadi, ...
Cell metabolism 4 (4), 291-302, 2006
SIRT4 Is a Lysine Deacylase that Controls Leucine Metabolism and Insulin Secretion
KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ...
Cell Metabolism 25 (4), 838-855. e15, 2017
Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
K Burkewitz, I Morantte, HJM Weir, R Yeo, Y Zhang, FK Huynh, ...
Cell 160 (5), 842-855, 2015
Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling
HJ Weir, P Yao, FK Huynh, CC Escoubas, RL Goncalves, K Burkewitz, ...
Cell metabolism 26 (6), 884-896. e5, 2017
The role of leptin in glucose homeostasis
HC Denroche, FK Huynh, TJ Kieffer
Journal of diabetes investigation 3 (2), 115-129, 2012
Leptin therapy reverses hyperglycemia in mice with streptozotocin-induced diabetes, independent of hepatic leptin signaling
HC Denroche, J Levi, RD Wideman, RM Sequeira, FK Huynh, SD Covey, ...
Diabetes 60 (5), 1414-1423, 2011
Measurement of fatty acid oxidation rates in animal tissues and cell lines
FK Huynh, MF Green, TR Koves, MD Hirschey
Methods in enzymology 542, 391-405, 2014
Disruption of hepatic leptin signaling protects mice from age-and diet-related glucose intolerance
FK Huynh, J Levi, HC Denroche, SL Gray, PJ Voshol, UH Neumann, ...
Diabetes 59 (12), 3032-3040, 2010
Acute disruption of leptin signaling in vivo leads to increased insulin levels and insulin resistance
J Levi, SL Gray, M Speck, FK Huynh, SL Babich, WT Gibson, TJ Kieffer
Endocrinology 152 (9), 3385-3395, 2011
Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH
AS Madsen, C Andersen, M Daoud, KA Anderson, JS Laursen, ...
Journal of Biological Chemistry 291 (13), 7128-7141, 2016
SnapShot: mammalian sirtuins
KA Anderson, MF Green, FK Huynh, GR Wagner, MD Hirschey
Cell 159 (4), 956-956. e1, 2014
A role for hepatic leptin signaling in lipid metabolism via altered very low density lipoprotein composition and liver lipase activity in mice
FK Huynh, UH Neumann, Y Wang, B Rodrigues, TJ Kieffer, SD Covey
Hepatology 57 (2), 543-554, 2013
Targeting sirtuins for the treatment of diabetes
FK Huynh, KA Hershberger, MD Hirschey
Diabetes management (London, England) 3 (3), 245, 2013
Hepatic leptin signalling and subdiaphragmatic vagal efferents are not required for leptin-induced increases of plasma IGF binding protein-2 (IGFBP-2) in ob/ob mice
J Levi, FK Huynh, HC Denroche, UH Neumann, MM Glavas, SD Covey, ...
Diabetologia 55 (3), 752-762, 2012
Loss of sirtuin 4 leads to elevated glucose-and leucine-stimulated insulin levels and accelerated age-induced insulin resistance in multiple murine genetic backgrounds
FK Huynh, X Hu, Z Lin, JD Johnson, MD Hirschey
Journal of Inherited Metabolic Disease 41 (1), 59-72, 2018
SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control
FK Huynh, DM Muoio, MD Hirschey
Diabetes 64 (9), 3058-3060, 2015
Cellular energetics and mitochondrial uncoupling in canine aging
JW Nicholatos, TM Robinette, SVP Tata, JD Yordy, AB Francisco, ...
GeroScience 41 (2), 229-242, 2019
Quantifying competition among mitochondrial protein acylation events induced by ethanol metabolism
HR Ali, MA Assiri, PS Harris, CR Michel, Y Yun, JO Marentette, FK Huynh, ...
Journal of proteome research 18 (4), 1513-1531, 2019
Deacetylation by SIRT3 Relieves Inhibition of Mitochondrial Protein Function
P Chhoy, KA Anderson, KA Hershberger, FK Huynh, AS Martin, ...
Sirtuins, 105-138, 2016
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα
S Naiman, FK Huynh, R Gil, Y Glick, Y Shahar, N Touitou, L Nahum, ...
Cell reports 29 (12), 4127-4143. e8, 2019
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