Tracy Nero
Tracy Nero
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Cited by
Oncogenic protein interfaces: small molecules, big challenges
TL Nero, CJ Morton, JK Holien, J Wielens, MW Parker
Nature Reviews Cancer 14 (4), 248-262, 2014
The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signaling
SE Broughton, U Dhagat, TR Hercus, TL Nero, MA Grimbaldeston, ...
Immunological reviews 250 (1), 277-302, 2012
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites
D Braig, TL Nero, HG Koch, B Kaiser, X Wang, JR Thiele, CJ Morton, ...
Nature communications 8 (1), 14188, 2017
Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA
DB Ascher, J Wielens, TL Nero, L Doughty, CJ Morton, MW Parker
Scientific reports 4 (1), 4765, 2014
Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators
U Flierl, TL Nero, B Lim, JF Arthur, Y Yao, SM Jung, E Gitz, AY Pollitt, ...
Journal of Experimental Medicine 212 (2), 129-137, 2015
Signalling by the βc family of cytokines
TR Hercus, U Dhagat, WLT Kan, SE Broughton, TL Nero, M Perugini, ...
Cytokine & growth factor reviews 24 (3), 189-201, 2013
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms
SL Pinkosky, JW Scott, EM Desjardins, BK Smith, EA Day, RJ Ford, ...
Nature metabolism 2 (9), 873-881, 2020
The βc receptor family–Structural insights and their functional implications
SE Broughton, TL Nero, U Dhagat, WL Kan, TR Hercus, D Tvorogov, ...
Cytokine 74 (2), 247-258, 2015
Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription
D Thomas, JA Powell, F Vergez, DH Segal, NYN Nguyen, A Baker, ...
Blood, The Journal of the American Society of Hematology 122 (5), 738-748, 2013
Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)
CJ Burns, DG Bourke, L Andrau, X Bu, SA Charman, AC Donohue, ...
Bioorganic & medicinal chemistry letters 19 (20), 5887-5892, 2009
Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
MR Morrow, B Batchuluun, J Wu, E Ahmadi, JM Leroux, ...
Cell Metabolism 34 (6), 919-936. e8, 2022
Repurposing of drugs as STAT3 inhibitors for cancer therapy
PS Thilakasiri, RS Dmello, TL Nero, MW Parker, M Ernst, AL Chand
Seminars in cancer biology 68, 31-46, 2021
Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8α and C9
SE Wickham, EM Hotze, AJ Farrand, G Polekhina, TL Nero, S Tomlinson, ...
Journal of Biological Chemistry 286 (23), 20952-20962, 2011
Small molecule binding to Alzheimer risk factor CD33 promotes Aβ phagocytosis
LA Miles, SJ Hermans, GAN Crespi, JH Gooi, L Doughty, TL Nero, ...
Iscience 19, 110-118, 2019
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody
SE Broughton, TR Hercus, MP Hardy, BJ McClure, TL Nero, M Dottore, ...
Cell reports 8 (2), 410-419, 2014
Conformational changes in the GM-CSF receptor suggest a molecular mechanism for affinity conversion and receptor signaling
SE Broughton, TR Hercus, TL Nero, M Dottore, BJ McClure, U Dhagat, ...
Structure 24 (8), 1271-1281, 2016
Evaluating the benefits of renin-angiotensin system inhibitors as cancer treatments
MV Perini, RS Dmello, TL Nero, AL Chand
Pharmacology & therapeutics 211, 107527, 2020
Discovery and SAR of novel pyrazolo [1, 5-a] pyrimidines as inhibitors of CDK9
LJ Phillipson, DH Segal, TL Nero, MW Parker, S San Wan, M de Silva, ...
Bioorganic & Medicinal Chemistry 23 (19), 6280-6296, 2015
Lysophosphatidylcholine is a major component of platelet microvesicles promoting platelet activation and reporting atherosclerotic plaque instability
P Diehl, F Nienaber, MTK Zaldivia, J Stamm, PM Siegel, NA Mellett, ...
Thrombosis and Haemostasis 119 (08), 1295-1310, 2019
Role of the β Common (βc) Family of Cytokines in Health and Disease
TR Hercus, WLT Kan, SE Broughton, D Tvorogov, HS Ramshaw, ...
Cold Spring Harbor Perspectives in Biology 10 (6), a028514, 2018
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