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Derin Keskin
Derin Keskin
Dana Farber Cancer Institute
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
An immunogenic personal neoantigen vaccine for patients with melanoma
PA Ott, Z Hu, DB Keskin, SA Shukla, J Sun, DJ Bozym, W Zhang, A Luoma, ...
Nature 547 (7662), 217-221, 2017
24922017
Potential regulatory function of human dendritic cells expressing indoleamine 2, 3-dioxygenase
DH Munn, MD Sharma, JR Lee, KG Jhaver, TS Johnson, DB Keskin, ...
Science 297 (5588), 1867-1870, 2002
13022002
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ...
Nature 565 (7738), 234-239, 2019
10832019
Mass spectrometry profiling of HLA-associated peptidomes in mono-allelic cells enables more accurate epitope prediction
JG Abelin, DB Keskin, S Sarkizova, CR Hartigan, W Zhang, J Sidney, ...
Immunity 46 (2), 315-326, 2017
5742017
Cells expressing indoleamine 2, 3-dioxygenase inhibit T cell responses
AL Mellor, DB Keskin, T Johnson, P Chandler, DH Munn
The Journal of Immunology 168 (8), 3771-3776, 2002
4602002
TGFβ promotes conversion of CD16+ peripheral blood NK cells into CD16− NK cells with similarities to decidual NK cells
DB Keskin, DSJ Allan, B Rybalov, MM Andzelm, JNH Stern, HD Kopcow, ...
Proceedings of the National Academy of Sciences 104 (9), 3378-3383, 2007
4442007
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
M Rajasagi, SA Shukla, EF Fritsch, DB Keskin, D DeLuca, E Carmona, ...
Blood, The Journal of the American Society of Hematology 124 (3), 453-462, 2014
4372014
A review of the current use of rituximab in autoimmune diseases
HM Gürcan, DB Keskin, JNH Stern, MA Nitzberg, H Shekhani, AR Ahmed
International immunopharmacology 9 (1), 10-25, 2009
4022009
A large peptidome dataset improves HLA class I epitope prediction across most of the human population
S Sarkizova, S Klaeger, PM Le, LW Li, G Oliveira, H Keshishian, ...
Nature biotechnology 38 (2), 199-209, 2020
3702020
Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells
F Fallarino, C Vacca, C Orabona, ML Belladonna, R Bianchi, B Marshall, ...
International Immunology 14 (1), 65-68, 2002
3342002
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma
Z Hu, DE Leet, RL Allesøe, G Oliveira, S Li, AM Luoma, J Liu, J Forman, ...
Nature medicine 27 (3), 515-525, 2021
2942021
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma
G Oliveira, K Stromhaug, S Klaeger, T Kula, DT Frederick, PM Le, ...
Nature 596 (7870), 119-125, 2021
2762021
Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery
Z Zhang, S Tongchusak, Y Mizukami, YJ Kang, T Ioji, M Touma, ...
Biomaterials 32 (14), 3666-3678, 2011
2712011
Mitochondrial reprogramming underlies resistance to BCL-2 inhibition in lymphoid malignancies
R Guièze, VM Liu, D Rosebrock, AA Jourdain, M Hernández-Sánchez, ...
Cancer cell 36 (4), 369-384. e13, 2019
2602019
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
DA Braun, K Street, KP Burke, DL Cookmeyer, T Denize, CB Pedersen, ...
Cancer Cell 39 (5), 632-648. e8, 2021
2552021
Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
DK Das, Y Feng, RJ Mallis, X Li, DB Keskin, RE Hussey, SK Brady, ...
Proceedings of the National Academy of Sciences 112 (5), 1517-1522, 2015
2372015
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer
T Ouspenskaia, T Law, KR Clauser, S Klaeger, S Sarkizova, F Aguet, B Li, ...
Nature biotechnology 40 (2), 209-217, 2022
1762022
Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy
SH Gohil, JB Iorgulescu, DA Braun, DB Keskin, KJ Livak
Nature Reviews Clinical Oncology 18 (4), 244-256, 2021
1672021
Developmental bias in cleavage-stage mouse blastomeres
I Tabansky, A Lenarcic, RW Draft, K Loulier, DB Keskin, J Rosains, ...
Current Biology 23 (1), 21-31, 2013
1592013
Indoleamine 2, 3-dioxygenase, immunosuppression and pregnancy
AL Mellor, P Chandler, GK Lee, T Johnson, DB Keskin, J Lee, DH Munn
Journal of reproductive immunology 57 (1-2), 143-150, 2002
1452002
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