Tom Mikkelsen
Tom Mikkelsen
Ontario Brain Institute
Verified email at braininstitute.ca
Title
Cited by
Cited by
Year
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network
Nature 455 (7216), 1061, 2008
51612008
The somatic genomic landscape of glioblastoma
CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ...
Cell 155 (2), 462-477, 2013
26662013
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
PY Wen, DR Macdonald, DA Reardon, TF Cloughesy, AG Sorensen, ...
Journal of clinical oncology 28 (11), 1963-1972, 2010
25702010
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
HS Friedman, MD Prados, PY Wen, T Mikkelsen, D Schiff, LE Abrey, ...
J clin oncol 27 (28), 4733-4740, 2009
22632009
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
Cancer Genome Atlas Research Network
New England Journal of Medicine 372 (26), 2481-2498, 2015
14452015
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
12052012
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ...
Cell 164 (3), 550-563, 2016
9342016
Clonal expansion of p53 mutant cells is associated with brain tumour progression
D Sidransky, T Mikkelsen, K Schwechheimer, ML Rosenblum, ...
Nature 355 (6363), 846-847, 1992
7871992
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
7002018
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
L Sun, AM Hui, Q Su, A Vortmeyer, Y Kotliarov, S Pastorino, A Passaniti, ...
Cancer cell 9 (4), 287-300, 2006
6922006
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
6172018
Transforming fusions of FGFR and TACC genes in human glioblastoma
D Singh, JM Chan, P Zoppoli, F Niola, R Sullivan, A Castano, EM Liu, ...
Science 337 (6099), 1231-1235, 2012
5422012
Oncogenic signaling pathways in the cancer genome atlas
F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ...
Cell 173 (2), 321-337. e10, 2018
5042018
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
DA Reardon, KL Fink, T Mikkelsen, TF Cloughesy, A O'Neill, S Plotkin, ...
Journal of Clinical Oncology 26 (34), 5610-5617, 2008
4942008
The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
ME Linskey, DW Andrews, AL Asher, SH Burri, D Kondziolka, ...
Journal of neuro-oncology 96 (1), 45-68, 2010
4832010
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer
KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ...
Cell 173 (2), 291-304. e6, 2018
4462018
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
NJ Szerlip, A Pedraza, D Chakravarty, M Azim, J McGuire, Y Fang, ...
Proceedings of the National Academy of Sciences 109 (8), 3041-3046, 2012
4432012
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ...
Cell 173 (2), 400-416. e11, 2018
4142018
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant …
EA Chiocca, KM Abbed, S Tatter, DN Louis, FH Hochberg, F Barker, ...
Molecular Therapy 10 (5), 958-966, 2004
4062004
New brain tumor entities emerge from molecular classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
3772016
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