Mitch A. Phelps
Mitch A. Phelps
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Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia
JC Byrd, TS Lin, JT Dalton, D Wu, MA Phelps, B Fischer, M Moran, ...
Blood 109 (2), 399-404, 2007
Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease
TS Lin, AS Ruppert, AJ Johnson, B Fischer, NA Heerema, LA Andritsos, ...
Journal of Clinical Oncology 27 (35), 6012, 2009
Multi-institutional phase II study of selumetinib in patients with metastatic biliary cancers
T Bekaii-Saab, MA Phelps, X Li, M Saji, L Goff, JSW Kauh, BH O'Neil, ...
Journal of clinical oncology 29 (17), 2357, 2011
miR-221 silencing blocks hepatocellular carcinoma and promotes survival
JK Park, T Kogure, GJ Nuovo, J Jiang, L He, JH Kim, MA Phelps, ...
Cancer research 71 (24), 7608-7616, 2011
Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats
W Gao, PJ Reiser, CC Coss, MA Phelps, JD Kearbey, DD Miller, ...
Endocrinology 146 (11), 4887-4897, 2005
Favorable effects of weak acids on negative-ion electrospray ionization mass spectrometry
Z Wu, W Gao, MA Phelps, D Wu, DD Miller, JT Dalton
Analytical chemistry 76 (3), 839-847, 2004
Clinical response and pharmacokinetics from a phase 1 study of an active dosing schedule of flavopiridol in relapsed chronic lymphocytic leukemia
MA Phelps, TS Lin, AJ Johnson, E Hurh, DM Rozewski, KL Farley, D Wu, ...
Blood, The Journal of the American Society of Hematology 113 (12), 2637-2645, 2009
Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others
JP Kitzmiller, DK Groen, MA Phelps, W Sadee
Cleveland Clinic journal of medicine 78 (4), 243, 2011
REO-10: a phase I study of intravenous reovirus and docetaxel in patients with advanced cancer
C Comins, J Spicer, A Protheroe, V Roulstone, K Twigger, CM White, ...
Clinical cancer research 16 (22), 5564-5572, 2010
Discovery and mechanism of highly efficient cyclic cell-penetrating peptides
Z Qian, A Martyna, RL Hard, J Wang, G Appiah-Kubi, C Coss, MA Phelps, ...
Biochemistry 55 (18), 2601-2612, 2016
Dose escalation of lenalidomide in relapsed or refractory acute leukemias
W Blum, RB Klisovic, H Becker, X Yang, DM Rozewski, MA Phelps, ...
Journal of clinical oncology 28 (33), 4919, 2010
Modeling of active transport systems
EY Zhang, MA Phelps, C Cheng, S Ekins, PW Swaan
Advanced drug delivery reviews 54 (3), 329-354, 2002
Topology scanning and putative three-dimensional structure of the extracellular binding domains of the apical sodium-dependent bile acid transporter (SLC10A2)
EY Zhang, MA Phelps, A Banerjee, CM Khantwal, C Chang, F Helsper, ...
Biochemistry 43 (36), 11380-11392, 2004
Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines
MA Bill, C Nicholas, TA Mace, JP Etter, C Li, EB Schwartz, JR Fuchs, ...
PloS one 7 (8), e40724, 2012
Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: Evidence for lenalidomide–CCI-779 interaction via P-glycoprotein
CC Hofmeister, X Yang, F Pichiorri, P Chen, DM Rozewski, AJ Johnson, ...
Journal of clinical oncology 29 (25), 3427, 2011
Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells
X Zhu, M Badawi, S Pomeroy, DS Sutaria, Z Xie, A Baek, J Jiang, ...
Journal of Extracellular Vesicles 6 (1), 1324730, 2017
Discovery of anticancer agents of diverse natural origin
AD Kinghorn, EJC De Blanco, DM Lucas, HL Rakotondraibe, J Orjala, ...
Anticancer research 36 (11), 5623-5637, 2016
Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples
GJ Nuovo, M Garofalo, N Valeri, V Roulstone, S Volinia, DE Cohn, ...
Modern Pathology 25 (10), 1333-1344, 2012
Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition
W Ni, J Ji, Z Dai, A Papp, AJ Johnson, S Ahn, KL Farley, TS Lin, JT Dalton, ...
PLoS One 5 (11), e13792, 2010
Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: a randomized phase 1 study
R Molokie, D Lavelle, M Gowhari, M Pacini, L Krauz, J Hassan, V Ibanez, ...
PLoS medicine 14 (9), e1002382, 2017
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